Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 4,440 | 5日内发货 | ||
500 μg | ¥ 17,800 | 5日内发货 | ||
1 mg | ¥ 29,600 | 5日内发货 |
生物活性 | Immobilized Canine GDF15, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 48.3ng/ml determined by ELISA. |
产品描述 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |
种属 | Canine |
表达系统 | E. coli |
标签 | N-His |
蛋白编号 | A0A8C0TNP6 |
别名 | GDF15, MIC1, MIC-1, PLAB, GDF-15, PDF, PTGFB, PTGF-beta, RG-1, Placental TGF-β, PTGF-β, PTGFBPTGF-beta, NAG-1, Placental TGF-beta, PTGFBPTGF-β |
蛋白构建 | Recombinant Canine GDF15 Protein is expressed from E.coli with His tag at the N-Terminus. It contains Ala197-Val307.[Accession |A0A8C0TNP6] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | The protein has a predicted MW of 13.12 kDa. The protein migrates to 15-20 kDa under reduced (R) condition and 23-26 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in 50mM HAc (pH 2.9). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM HAc (pH 2.9). |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |
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GDF-15 Protein, Canine, Recombinant (His) GDF15 MIC1 MIC-1 RG 1 NAG1 PLAB PTGFBPTGF-b RG1 NAG 1 GDF-15 PDF PTGFB PTGF-b PTGF-beta RG-1 Placental TGF-β PTGF-β Placental TGF-b PTGFBPTGF-beta NAG-1 Placental TGF-beta GDF 15 PTGFBPTGF-β MIC 1 recombinant recombinant-proteins proteins protein