目录号 | 产品详情 | 靶点 | |
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T27323 | Adenosine Receptor | ||
FK-453 是一种有效的非黄嘌呤腺苷 A1 受体拮抗剂,具有利尿和肾血管扩张活性。 | |||
T33676 | Xanthine Oxidase | ||
Niraxostat (Y-700) 是作为黄嘌呤氧化酶抑制剂的异胞嘧啶衍生物之一。 | |||
T1363 | ROS | ||
N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) 被报道为 xanthine oxidase 抑制剂。 | |||
T8567 | Xanthine Oxidase | ||
amflutizole 用于治疗痛风,是一种黄嘌呤氧化酶抑制剂。 | |||
T20102 | Nucleoside Antimetabolite/Analog | ||
8-Azahypoxanthine (NSC-22709) 抑制次黄嘌呤-鸟嘌呤-黄嘌呤磷酸核糖基转移酶并具有抗疟特性。 | |||
T68145 | |||
Stacofylline 是一种黄嘌呤衍生物,可用于治疗偏头疼。 | |||
T9366 | ROS | ||
Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) 是人黄嘌呤氧化酶的抑制剂。 | |||
T60625 | |||
Tigulixostat 是吲哚基杂芳羧酸的新型衍生物。Tigulixostat 是一种非嘌呤选择性的黄嘌呤氧化酶抑制剂,可降低尿酸的生成。 | |||
T0543 | Nucleoside Antimetabolite/Analog Endogenous Metabolite | ||
7-Methylxanthine (Heteroxanthine) 是一种黄嘌呤的甲基衍生物,是人尿结石的嘌呤成分。 | |||
T5S0281 | NOS | ||
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-02464 | Catalase/CAT Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells | ||
Catalase is a ubiquitously expressed enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a tetramer of four polypeptides chains containing four porphyrin heme groups that allow the enzyme to react with the hydrogen peroxide. The optimum PH of human catalase is approximately 7 and the optimum temperature is at 37 degree. Both the PH optimum and temperature for other catalases varies depending on the species. Catalase can be inhibited by a flux of O2-generated in situ by the aerobic xanthine oxidase reaction. This inhibition of catalase by O2-provides the basis for a synergism between superoxide dismutase and catalase.Such synergisms have been observed in vitro and may be significant in vivo. Catalase is used in the food industry for removing hydrogen peroxide from milk prior to cheese production. Another use is in food wrappers where it prevents food from oxidizing. Catalase is also used in the textile industry, removing hydrogen peroxide from fabrics to make sure the material is peroxide-free.
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TMPJ-00764 | Catalase/CAT Protein, Human, Recombinant | Human | E. coli | ||
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells, and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of catalase activity in red cells and is associated with ulcerating oral lesions.
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