目录号 | 产品详情 | 靶点 | |
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T2S0799 | Tyrosinase | ||
Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 melanoma cells. | |||
T40846 | |||
3,5-Difluoro-L-tyrosine is a functional and tyrosinase-resistant mimic of tyrosine, commonly utilized for evaluating the substrate specificity of protein tyrosine phosphatases (PTPs). | |||
TN3504 | Others | ||
beta-Hydroxypropiovanillone, an achiral compound, which is further degraded by lignin degradation. It shows tyrosinase inhibitory activities. | |||
TN2303 | Tyrosinase | ||
Viscumneoside III 是一种二氢黄酮 O-糖苷,抑制酪氨酸酶 (tyrosinase),IC50 为 0.5 mM。Viscumneoside III 具有抗心绞痛作用。 | |||
T75572 | |||
Obtusifolin-2-O-glucoside (化合物 7) 作为一种酪氨酸酶 (Tyrosinase) 抑制剂,其IC50值为9.2 μM,可从决明子种子中提取。 | |||
TMA2563 | Tyrosinase | ||
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors. | |||
TN4179 | ERK Tyrosinase Akt | ||
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of tyrosinase and TRP-1 production. Hag | |||
TN6556 | |||
Safflospermidine B is a potential natural tyrosinase inhibitor, it shows high antityrosinase activity (IC50 of 31.8μM). | |||
T30048 | |||
Anemonin is a furanone dimer found in the Buttercup (Ranunculaceae) family. Anemonin has been shown to regulate tyrosinase-related proteins and mRNA in human melanocytes and may be useful in attenuting osteoarthritis progression. | |||
TP1675 | |||
This peptide is a TRP-tyrosinase-related protein. Its immunization results in effective induction of antitumor immunity. |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPH-02269 | Tyrosinase/TYR Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) | ||
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
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TMPH-02270 | Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
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TMPH-02751 | DCT Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli | ||
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). DCT Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 69.7 kDa and the accession number is P29812.
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TMPH-01608 | DCT Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli | ||
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
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