T16623
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Propargyl-PEG4-CH2-methyl ester
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Propargyl-PEG4-CH2-methyl ester is a PEGylated linker compound utilized for the synthesis of PROTACs.
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T17490
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Azido-PEG16-Boc
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Azido-PEG16-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T16049
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Methylamino-PEG2-acid
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Methylamino-PEG2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T15494
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HO-PEG8-CH2CH2COOH
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Hydroxy-PEG8-acid (HO-PEG8-CH2CH2COOH) is a PEG-based PROTAC linker employed for PROTAC synthesis[1].
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T17424
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Amino-PEG25-acid
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Amino-PEG25-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14234
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Amino-PEG3-C2-Azido
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Amino-PEG3-C2-Azido is a polyethylene glycol (PEG)-based linker used in the synthesis of iRucaparib-TP3, a PARP1 degrader [1].
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T16650
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Propargyl-PEG8-bromide
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Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
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T18311
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Mc-MMAD
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Mc-MMAD, a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporates the protective group maleimidocaproyl (Mc) conjugated to monomethyl auristatin D (MMAD), a potent inhibitor of tubulin.
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T18342
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Methyltetrazine-PEG13-NHS ester
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Methyltetrazine-PEG13-NHS ester is a polyethylene glycol (PEG)-derived linker, designed specifically for use in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
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T15867
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m-PEG4-aldehyde
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m-PEG4-aldehyde is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T15832
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m-PEG-OH (MW 2000)
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m-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
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T14599
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Biotin-PEG4-amine
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Biotin-PEG4-amine is a biotinylated, PEGylated amine linker utilized in PROTAC synthesis[1].
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T17900
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cIAP1 Ligand-Linker Conjugates 8
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cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].
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T16242
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N-(PEG1-OH)-N-Boc-PEG2-propargyl
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N-(PEG1-OH)-N-Boc-PEG2-propargyl is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
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T15898
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m-PEG5-phosphonic acid ethyl ester
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m-PEG5-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-derived linker commonly employed in the construction of proteolysis targeting chimeras (PROTACs)[1].
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T17429
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Amino-PEG36-acid
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Amino-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18173
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m-PEG25-acid
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m-PEG25-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T16643
|
Propargyl-PEG6-NH2
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Propargyl-PEG6-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14018
|
(2-Pyridyldithio)-PEG2-Boc
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(2-Pyridyldithio)-PEG2-Boc is a polyethylene glycol-based PROTAC linker utilized for the synthesis of PROTACs[1].
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T16604
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Propargyl-PEG2-Tos
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Propargyl-PEG2-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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