T17457
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Azide-PEG-amine (MW 2000)
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Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG) derived linker compound utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
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T15913
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m-PEG6-CH2CH2CHO
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m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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T14600
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Biotin-PEG4-methyltetrazine
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Biotin-PEG4-methyltetrazine is a PEG-derived linker utilized for synthesizing PROTACs[1], a type of molecule employed in targeted protein degradation.
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T18249
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Mal-C6-α-Amanitin
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Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.
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T14397
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Azide-PEG5-Tos
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Azide-PEG5-Tos is a cleavable PEG linker consisting of five units, employed for the synthesis of antibody-drug conjugates (ADCs)[1].
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T18036
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Hydroxy-PEG12-CH2-Boc
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Hydroxy-PEG12-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T17392
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Amine-PEG-amine (MW 3400)
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Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
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T17138
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Tos-PEG6-OH
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Tos-PEG6-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18491
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NH2-PEG4-Lys(Boc)-NH-(m-PEG24)
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NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker containing a cleavable bond, commonly employed in the production of antibody-drug conjugates (ADCs)[1].
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T18343
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Methyltetrazine-PEG24-amine
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Methyltetrazine-PEG24-amine is a PEG-conjugated PROTAC linker utilized for the synthesis of PROTACs[1].
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T17827
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Diketone-PEG12-DBCO
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Diketone-PEG12-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T16624
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Propargyl-PEG4-CH2CH2-Boc
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Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
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T15972
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Mal-NH2 TFA
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Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T17635
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Bis-Tos-PEG6
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Bis-Tos-PEG6 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14246
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Amino-PEG5-CH2COOH
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Amino-PEG5-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T15149
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DNP-NH-PEG4-C2-Boc
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DNP-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14398
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Azide-PEG6-Tos
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Azide-PEG6-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T15875
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m-PEG4-CH2-acid
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m-PEG4-CH2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18306
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MC-Alkyl-Hydrazine Modified MMAF
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MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1].
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T14803
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Bromo-PEG4-bromide
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Bromo-PEG4-bromide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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