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Linker

产品编号 产品名称
T17457 Azide-PEG-amine (MW 2000) Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG) derived linker compound utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T15913 m-PEG6-CH2CH2CHO m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
T14600 Biotin-PEG4-methyltetrazine Biotin-PEG4-methyltetrazine is a PEG-derived linker utilized for synthesizing PROTACs[1], a type of molecule employed in targeted protein degradation.
T18249 Mal-C6-α-Amanitin Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.
T14397 Azide-PEG5-Tos Azide-PEG5-Tos is a cleavable PEG linker consisting of five units, employed for the synthesis of antibody-drug conjugates (ADCs)[1].
T18036 Hydroxy-PEG12-CH2-Boc Hydroxy-PEG12-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17392 Amine-PEG-amine (MW 3400) Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
T17138 Tos-PEG6-OH Tos-PEG6-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18491 NH2-PEG4-Lys(Boc)-NH-(m-PEG24) NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker containing a cleavable bond, commonly employed in the production of antibody-drug conjugates (ADCs)[1].
T18343 Methyltetrazine-PEG24-amine Methyltetrazine-PEG24-amine is a PEG-conjugated PROTAC linker utilized for the synthesis of PROTACs[1].
T17827 Diketone-PEG12-DBCO Diketone-PEG12-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16624 Propargyl-PEG4-CH2CH2-Boc Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
T15972 Mal-NH2 TFA Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17635 Bis-Tos-PEG6 Bis-Tos-PEG6 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14246 Amino-PEG5-CH2COOH Amino-PEG5-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15149 DNP-NH-PEG4-C2-Boc DNP-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14398 Azide-PEG6-Tos Azide-PEG6-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15875 m-PEG4-CH2-acid m-PEG4-CH2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18306 MC-Alkyl-Hydrazine Modified MMAF MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1].
T14803 Bromo-PEG4-bromide Bromo-PEG4-bromide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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