目录号 | 产品详情 | 靶点 | |
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T5980 | Tyrosinase Endogenous Metabolite | ||
2-Ketoglutaric acid 是 Krebs 循环的中间体,可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。 | |||
TN1296 | Tyrosinase Sirtuin | ||
5-Feruloylquinic acid (5-FQA) 表现出抗氧化作用和酪氨酸酶抑制作用。 | |||
T2A2524 | Tyrosinase Antibacterial | ||
2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) 是一种来自三种东非药用植物,Mondia whitei、Rhus vulgaris Meikle 和Sclerocarya caffra Sond 的酪氨酸酶抑制剂。它是香兰素的异构体,可用于合成尿苷M7。 | |||
T3737 | Tyrosinase | ||
3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂,可抑制 L-Tyrosine 和 DL-DOPA,IC50和 Ki 分别为 3.02 μM 和 11.5 μM。 | |||
T61460 | |||
Tyrosinase-IN-3 (compound 54) is a powerful tyrosinase inhibitor, an enzyme involved in the key catalytic step of melanin biosynthesis and enzymatic browning. As a copper-containing metalloenzyme, tyrosinase plays a crucial role in these processes. The compound shows promise for studying skin whitening agents and food preservatives [1]. | |||
T72720 | |||
Tyrosinase-IN-10 是一种部分竞争性酪氨酸酶 (tyrosinase) 抑制剂,其 IC50为 1.6 μM,可抑制人黑素瘤细胞裂解物中的酪氨酸酶活性。 | |||
T72786 | |||
Tyrosinase-IN-7,以IC50值为1.57 µM,为一种有效的酪氨酸酶抑制剂,并且展现低细胞毒性地抑制细胞生长。 | |||
T3745 | Tyrosinase | ||
3,4-Dimethoxyphenol (4-Hydroxyveratrole) 是一种植物来源的苯基丙烷化合物,可在化妆品中用作增白剂。它可从细菌发酵液中分离出,有抗氧化作用。它具有酪氨酸酶抑制活性。 | |||
TCS1709 | Tyrosinase | ||
Benzylacetone (4-Phenyl-2-butanone) 是一种从沉香木中提取的芳香族化合物。它具有增强食欲和减少运动的作用。它具有较强且可逆的抗蘑菇酪氨酸酶作用,对单酚酶和双酚酶作用的IC50值分别为 2.8 mM 和 0.6 mM。 | |||
T74243 | |||
Tyrosinase/elastase-IN-1,一种来源于悬钩子叶的三萜类化合物,具有抑制酪氨酸酶和弹性蛋白酶活性的功能。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPH-02269 | Tyrosinase/TYR Protein, Human, Recombinant (His) | Human | Yeast | ||
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
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TMPH-02270 | Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
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TMPH-02751 | DCT Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli | ||
DCT Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
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TMPH-01608 | DCT Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli | ||
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
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