T22404
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Others
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Pralidoxime Iodide, also named 2-PAM, is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning. |
T69079
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Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning. |
T31370
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Delparantag( PMX-60056) is a heparins antidote designed to restore coagulation. |
T16372
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Others
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Obidoxime dichloride, a selective oxime agent, effectively reactivates sarin-inhibited acetylcholinesterase (AChE) and mitigates the acute toxicity associated with sarin exposure. It is also utilized as an antidote for organophosphate nerve agent poisoning. |
T69472
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Edrophonium is a rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles. |
T62857
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K203 是一种有效的 tabun 抑制的 AChE 再激活剂,是一种重要的有机磷中毒解毒剂。 |
T61187
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BRD4 Inhibitor-17 (Compound 5i) is a highly potent inhibitor of BRD4, exhibiting an impressive IC50 value of 0.33 μM. It fulfills a crucial regulatory function in transcription by effectively modulating the expression of inflammatory, proliferation, and cell cycle genes. Moreover, BRD4 Inhibitor-17 shows promise as a potential remedy for arsenical-induced toxicity, thus highlighting its potential as an antidote in such cases [1]. |
T72245
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Fomepizole hydrochloride(4-Methylpyrazole)是一种高效、具口服活性的细胞色素P450(CYP2E1)和竞争性乙醇脱氢酶(alcohol dehydrogenase)抑制剂,阻止甲醇和乙二醇转化为有毒代谢产物,具有用于乙二醇或甲醇中毒解毒的潜力。 |
T73060
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Pralidoxime 是一种有效的乙酰胆碱酯酶 (AChE) 的再激活剂。Pralidoxime 通过肟部分对结合神经毒剂磷中心的亲核攻击,重新激活受神经毒剂抑制的 AChE。Pralidoxime 是一种有机磷中毒的解毒剂。 |