T35410
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(+)-Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 mouse leukemia cells and pesticidal activities. It has been shown to have promising cytotoxic activity against p388 mouse leukemia cells (ED50 ≥30 μg/ml). |
T62002
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Topoisomerase I inhibitor 7 (Compound 8) 是有效的Topoisomerase I 抑制剂。Topoisomerase I inhibitor 7 显著抑制肿瘤生长(高达 79%)。在接受 P388 淋巴瘤移植的小鼠模型中,Topoisomerase I inhibitor 7延长了小鼠寿命(153%)。 |
T26180
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Sdz 280 446 is one of the most active cyclopeptolide of many resistance-modifying agents in restoring rhodamine-123 retention within multidrug-resistant P388 cells. |
T34645
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Simetride is used in the Reversal of resistance to vincristine in P388 leukemia. |
T26413
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A 30312 is a fused indole, which overcomes multidrug resistance in P388/Adr cells in vitro. It potentiates the cytotoxicity of the antitumor drugs Adriamycin, vincristine and vinblastine in multidrug-resistant cells with no effect on drug-sensitive parent P388 cells. |
TMA0896
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Others
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Kulinone has cytotoxic effects, with IC50 values of 5.6-21.2 ug/mL, it inhibited (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line. |
TN4798
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Others
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Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM. |
T81052
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T988C为一种七环ETP(epidithiodioxopiperazine)天然产物,对P388白血病细胞系培养细胞显示出显著的细胞毒性。 |
T68184
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Saquayamycin B is a glycoside of aquayamycin that acts on Gram-positive bacteria and inhibits the growth of adriamycin-sensitive and adriamycin-resistant P388 leukemia cells. |
T68865
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Amoorastatin is a natural product that has been studied in cancer research. Its derivative was found to significantly inhibit growth of the murine P388 lymphocytic leukemia cell lines. |