目录号 | 产品详情 | 靶点 | |
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T78556 | Others | ||
Antidepressant agent 5 是一种具有抗抑郁活性的 7-取代四氢异喹啉衍生物。Antidepressant agent 5 在研究抑郁症方面和木兰花碱作用效果类似,可用于预防和治疗抑郁症疾病。 | |||
T10332 | Others | ||
Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. It also can be used to increase body temperature. | |||
T75003 | |||
Antidepressant agent 4为一种口服活性抗抑郁剂,具备抗抑郁、抗焦虑、性能增强以及促智活性。 | |||
T62495 | |||
Antidepressant agent 2 表现出明显的抗抑郁作用,其 MED 值为 0.1 mg/kg。 | |||
T75002 | |||
Antidepressant agent 3, 一种具有口服活性的抗抑郁剂,具备抗抑郁、抗焦虑、性能增强及促智活性。 | |||
T3856 | ERK Others | ||
Tenuifoliside A 是从远志分离得到的一种天然产物,具有抗凋亡、抗抑郁、抗炎和神经保护活性。 | |||
T3886 | P450 | ||
Rosavin (Rosavidin) 是从R. rosea 中获得的,在小鼠模型中表现出抗抑郁、适应原性和抗焦虑样作用。 | |||
T5661 | Others | ||
Methyl isoeugenol 是一种天然的食用香精,占石竹叶香精油的 93.7%。该物种的叶子提取物用作镇静剂。作为一种无处不在的食品添加剂,MIE 在治疗情绪障碍方面的应用。 | |||
T9787 | AChR | ||
SUVN-911 是高选择性的,大脑通透性的和口服有效的神经元烟碱乙酰胆碱 α4β2 受体拮抗剂,Ki 为 1.5 nM。SUVN-911显示出抗抑郁作用。 | |||
T3933 | MAO 5-HT Receptor Antibacterial AChE | ||
Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱,具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPH-00861 | HTR1D Protein, Human, Recombinant (His & KSI) | Human | E. coli | ||
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.
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TMPH-00860 | HTR1D Protein, Human, Recombinant (hFc) | Human | HEK293 | ||
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.
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TMPH-00859 | HTR1B Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system | ||
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
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