目录号 | 产品详情 | 靶点 | |
---|---|---|---|
T2O2774 | Endogenous Metabolite | ||
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。 | |||
T8392 | Endogenous Metabolite | ||
L(+)-Asparagine monohydrate 是一种非必需氨基酸,参与组织细胞功能的神经和代谢调节。 | |||
T4933 | Endogenous Metabolite | ||
(S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine),也称为acasn,属于一种内源性代谢产物。 | |||
TN3748 | Others Endogenous Metabolite | ||
D-Asparagine (H-D-Asn-OH) 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。 | |||
T37949 | |||
2,4-Dihydroxyphenylacetyl-L-asparagine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T37949,CAS号为 111872-98-1。 | |||
TP1115 | Others | ||
L-Asparaginase (L-ASNase) 是催化 L-天冬酰胺转化的水解酶,从血浆中去除 L-天冬酰胺,导致 RNA 和 DNA 合成抑制,随后引起细胞凋亡。它用于急性淋巴细胞白血病的研究。 | |||
T2O2731 | Others Endogenous Metabolite | ||
L-Aspartic acid (Aspatofort) 是一种氨基酸,是结肠特异性药物输送的前体药物。 | |||
T69829 | |||
GCN2iB is a GCN2 inhibitor. GCN2iB may be useful for the treatment of cancer. The inhibition of GCN2 sensitizes cancer cells with low basal-level expression of asparagine synthetase (ASNS) to the antileukemic agent L-asparaginase (ASNase) in vitro and in vivo. |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPH-01598 | CCBL2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).
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