T18708
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SPDP-C6-Gly-Leu-NHS ester
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SPDP-C6-Gly-Leu-NHS ester is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
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T16203
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N-Boc-N-bis(C2-PEG1-azide)
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N-Boc-N-bis(C2-PEG1-azide) is an alkyl/ether-based PROTAC linker suitable for synthesizing PROTACs[1].
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T18087
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m-PEG-CH2COOH (MW 2000)
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m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker, suitable for synthesizing PROTACs[1].
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T15332
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Fmoc-PEG4-NHS ester
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Fmoc-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T17077
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Thiol-PEG4-acid
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Thiol-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T17819
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Thalidomide-O-amido-C8-NH2
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Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of PROTACs, as per reference [1].
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T18208
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m-PEG49-NHS ester
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m-PEG49-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14793
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Bromo-PEG2-phosphonic acid diethyl ester
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Bromo-PEG2-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
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T18260
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Mal-NH-PEG6-CH2CH2COOPFP ester
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Mal-NH-PEG6-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker known as a PROTAC linker, designed specifically for the synthesis of PROTACs[1].
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T18521
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PC DBCO-PEG3-biotin
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PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker, specifically designed for antibody-drug conjugate (ADC) synthesis, with a cleavable moiety consisting of a dibenzocyclooctyne (DBCO) group and a biotin molecule. This linker provides a platform for the efficient attachment of drugs to antibodies, facilitating the targeted delivery and controlled release of therapeutic agents in ADCs[1].
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T17466
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Azide-PEG16-alcohol
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Azide-PEG16-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T16307
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NH-bis(PEG4-C2-NH-Boc)
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NH-bis(PEG4-C2-NH-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T17690
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Boc-Val-Ala-PAB-PNP
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Boc-Val-Ala-PAB-PNP is an ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1]. This cleavable compound efficiently facilitates the attachment of drugs to antibodies, allowing for targeted delivery and release of therapeutic agents within the body, making it an important component in ADC development.
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T17816
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DBCO-Val-Cit-PABC-PNP
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DBCO-Val-Cit-PABC-PNP is a cleavable linker for antibody-drug conjugate (ADC) synthesis[1].
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T16182
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].
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T17869
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cIAP1 ligand 2
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cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
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T18753
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TCO-PEG1-Val-Cit-OH
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TCO-PEG1-Val-Cit-OH is a cleavable 1-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
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T14772
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Br-PEG4-CH2-Boc
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Br-PEG4-CH2-Boc, a PEG- and Alkyl/ether-based PROTAC linker, serves as a valuable component for the synthesis of PROTACs[1].
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T17984
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Folate-PEG3-azide
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Folate-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18434
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N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5
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N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a polyethylene glycol (PEG) based PROTAC linker utilized for the synthesis of PROTACs[1].
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