T69358
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Others
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S101 is an inhibitor of proliferating T-cells, rescuing mice from superantigen-induced shock. |
T3516
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HDAC
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EDO-S101 (Tinostamustine) 是一种泛 HDAC 抑制剂,IC50为 6 nM,对 HDAC1、HDAC2 和 HDAC3 的 IC50 值分别为 9、9 和 25 nM。 |
T70189
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Others
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Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic. |
T70190
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Others
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Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents. |