|
TMPY-01041
|
VEGF165 Protein, Human/Cynomolgus, Recombinant
|
Human, Cynomolgus
|
Baculovirus Insect Cells
|
|
VEGF165 Protein, Human/Cynomolgus, Recombinant is expressed in Baculovirus Insect Cells expression system. The predicted molecular weight is 19.2 kDa and the accession number is P15692-4.
|
|
TMPY-00749
|
FGF-2 Protein, Human, Recombinant
|
Human
|
E. coli
|
|
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
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|
TMPJ-00864
|
VEGF165 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
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|
TMPK-00823
|
VEGF165 Protein, Human, Recombinant (His & Avi)
|
Human
|
HEK293 Cells
|
|
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
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TMPY-01033
|
IL-32 Protein, Human, Recombinant (isoform alpha, His)
|
Human
|
HEK293 Cells
|
|
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.
|
|
TMPY-04911
|
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human,Cynomolgus
|
HEK293 Cells
|
|
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
|
|
TMPY-00891
|
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
|
Human
|
HEK293 Cells
|
|
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
|
|
TMPY-02096
|
TACI Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
|
|
TMPY-04113
|
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
|
|
TMPY-02011
|
CD96 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
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|
TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are involved in the development of glioma (GLM). Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas , and ependymomas. DMBT1 may be considered as a candidate tumor suppressor for brain, lung, esophageal, gastric, and colorectal cancers. It may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. DMBT1 may play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. It may be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. DMBT1 may function as a binding protein in saliva for the regulation of taste sensation. It binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission.
|
|
TMPY-01717
|
VEGF164 Protein, Mouse, Recombinant
|
Mouse
|
Baculovirus Insect Cells
|
|
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
|
|
TMPY-00341
|
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
|
Human
|
HEK293 Cells
|
|
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
|
|
TMPY-01613
|
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
|
|
TMPJ-00850
|
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
|
Mouse
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
|
|
TMPY-03527
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
|
Human
|
HEK293 Cells
|
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa and the accession number is O14788-2.
|
|
TMPY-00701
|
CD16b Protein, Human, Recombinant (NA2, HEK293, His)
|
Human
|
HEK293 Cells
|
|
CD16b Protein, Human, Recombinant (NA2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2.
|
|
TMPY-01691
|
Clusterin Protein, Human, Recombinant (CLU34, His)
|
Human
|
HEK293 Cells
|
|
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
|
|
TMPY-00751
|
TrkB Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
|
|
TMPY-05288
|
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
|
Human
|
E. coli
|
|
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
|
|
TMPY-04844
|
BTN3A1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
|
|
TMPY-06056
|
KRAS Protein, Human, Recombinant (G12D, His)
|
Human
|
E. coli
|
|
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
|
|
TMPY-02820
|
SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)
|
Human
|
E. coli
|
|
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
|
|
TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
|
Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity and tau phosphorylation. c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. The c-Abl protein is a ubiquitously expressed nonreceptor tyrosine kinase involved in the development and function of many mammalian organ systems, including the immune system and bone. It regulates the cellular response to TAM through functional interaction with the estrogen receptor, which suggests c-Abl as a therapeutic target and a prognostic tumor marker for breast cancer. c-Abl also plays a key role in signaling chemokine-induced T-cell migration. In addition, c-Abl contains NLSs (nuclear localization signals) and DNA-binding sequences important for nuclear functions. c-Abl has become an important therapeutic target in human chronic myeloid leukaemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
|
|
TMPY-01935
|
c-Kit Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
|
|
TMPY-04644
|
PDGFB Protein, Human, Recombinant (His)
|
Human
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.
|
|
TMPY-04356
|
GSK3B Protein, Human, Recombinant (His)
|
Human
|
Baculovirus Insect Cells
|
|
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
|
|
TMPY-01985
|
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human
|
HEK293 Cells
|
|
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
|
|
TMPY-02500
|
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
|
|
TMPY-05414
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
|
Mouse
|
Baculovirus Insect Cells
|
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
|
|
TMPY-04424
|
MST3 Protein, Human, Recombinant (His)
|
Human
|
Baculovirus Insect Cells
|
|
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.
|
|
TMPY-01871
|
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
|
Human
|
HEK293 Cells
|
|
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
|
|
TMPY-02792
|
GDNF Protein, Human, Recombinant (HEK293)
|
Human
|
HEK293 Cells
|
|
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
|
|
TMPY-01359
|
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
|
|
TMPY-01888
|
KRAS Protein,Human, Recombinant (Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
|
|
TMPY-00747
|
Nectin-2 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
|
|
TMPY-04051
|
c-Kit Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
|
|
TMPY-05427
|
CD19 Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
|
|
TMPJ-00335
|
TGFBR2 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
|
|
TMPY-00127
|
M-CSF/CSF1 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
|
|
TMPY-02906
|
CD16b Protein, Human, Recombinant (NA2, CHO, His)
|
Human
|
CHO Cells
|
|
CD16b Protein, Human, Recombinant (NA2,His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2.
|
|
TMPY-04116
|
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
|
|
TMPY-02231
|
TrkB Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
|
|
TMPY-02432
|
VEGF164 Protein, Rat, Recombinant
|
Rat
|
Baculovirus Insect Cells
|
|
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
|
|
TMPY-00850
|
ST2/IL-1 RL1 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
|
|
TMPY-02367
|
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
|
Human
|
HEK293 Cells
|
|
Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
|
|
TMPY-00849
|
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
|
|
TMPY-04829
|
G-CSF Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
|
|
TMPY-00871
|
LAYN Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
|
|
TMPY-01199
|
CD74 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
|
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