目录号 | 产品详情 | 靶点 | |
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T63092 | Others | ||
Anti-inflammatory agent 12 是一种五环三萜化合物,在 LPS 诱导的炎症反应中表现出显着的偏差 (IC50: 2.22 μM)。Anti-inflammatory agent 12 具有潜力用于炎症性疾病的研究。 | |||
T72144 | Others | ||
6-trans-12-epi-Leukotriene B4 是一种花生四烯酸代谢物,是一种有效的抗炎剂。 | |||
T74327 | Others | ||
Antitumor agent-41 (compound N-12),一种具有卓越抗迁移及抗侵袭能力的抗肿瘤剂。通过坏死和炎症通路实现其抗肿瘤作用。 | |||
T74953 | Others | ||
Antimicrobial agent-7 (Compound 12) 为一化合物,对革兰氏阴性及革兰氏阳性菌展现出显著的抗菌能力,MIC值介于 2-8 μg/mL 之间。此外,该化合物还对脂多糖引发的炎症有着抗炎作用。 | |||
T60566 | Others | ||
COX-2-IN-12 (compound 3b) 是一种有效的选择性COX-2抑制剂,IC50值为 19.98 μM。COX-2-IN-12 是一种抗炎剂,并且在体内急性毒性研究中显示出安全性。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-02642 | UBE2W Protein, Human, Recombinant (His) | Human | E. coli | ||
Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It also catalyzes monoubiquitination and "Lys-11"-linked polyubiquitination. UBE2W is also considered to regulate FANCD2 monoubiquitination. UBE2W exhibits ubiquitin conjugating enzyme activity and catalyzes the monoubiquitination of PHD domain of Fanconi anemia complementation group L (FANCL). Over-expression of UBE2W in cells promotes the monoubiquitination of FANCD2 and down-regulated UBE2W markedly reduces the UV irradiation-induced but not MMC-induced FANCD2 monoubiquitination.
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TMPY-04620 | Neurofascin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells | ||
Neurofascin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-12.
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TMPY-00031 | Neuregulin-1/NRG1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12.
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TMPY-00479 | Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells | ||
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12.
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TMPY-03797 | Neurofascin Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Neurofascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.4 kDa and the accession number is O94856-12.
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