目录号 | 产品详情 | 靶点 | |
---|---|---|---|
T60970 | |||
Caprochlorone 对正痘病毒具有抗病毒活性,可以降低被感染的小鼠肺部中流感病毒的滴度。Caprochlorone 可以抑制病毒穿透细胞,并且延迟新形成的病毒从细胞释放。 | |||
T60876 | |||
HOE961 是 S2242 的二乙酸酯前药,具有抗正痘病毒活性。HOE961 在感染模型中具有口服活性。HOE961 对呼吸道牛痘病毒感染具有活性。 | |||
T63997 | |||
Mitoxantrone diacetate 是拓扑异构酶II (topoisomerase II) 的有效抑制剂。Mitoxantrone diacetate 也能够抑制蛋白激酶 C (PKC) (IC50: 8.5 μM)。Mitoxantrone diacetate 能够诱导 B-慢性淋巴细胞白血病 (B-CLL) 细胞凋亡 (apoptosis)。Mitoxantrone diacetate 表现出抗肿瘤作用,也具有抗正痘病毒 (orthopoxvirus) 效果,能够作用于牛痘 (EC50: 0.25 μM) 和猴痘 (EC50: 0.8 μM)。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
---|---|---|---|---|---|
TMPK-01253 | A35R Protein, Monkeypox virus, Recombinant (His) | Monkeypox virus | HEK293 | ||
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans.
|
|||||
TMPK-01123 | A29 Protein, Monkeypox virus, Recombinant (His) | Monkeypox virus | E. coli | ||
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans.
|
|||||
TMPK-01250 | M1R Protein, Monkeypox virus, Recombinant (His) | Monkeypox virus | HEK293 | ||
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans.
|
|||||
TMPK-01116 | A30 Protein, Monkeypox virus, Recombinant (His) | Monkeypox virus | HEK293 | ||
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A30L is an envelope protein required for the fusion of virus and host cell to form syncytia, and is also considered to be an important target in MPXV research.
|