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血小板源生长因子受体

血小板源生长因子受体 (Platelet-Derived Growth Factor Receptors, PDGFRs) 是血小板源生长因子(PDGF)家族成员的细胞表面酪氨酸激酶受体。PDGF亚基-A和-B是调节细胞增殖、细胞分化、细胞生长、发育和包括癌症在内的许多疾病的重要因素。PDGF-R有两种形式,α和β,每种形式由不同的基因编码。根据结合的生长因子,PDGF-R 同源或异源二聚化。对 RTKs 诱导的不同信号级联的检查确立了 Ras/MAPK、PI3K和PLCγ通路作为 PDGFR 信号转导的关键下游介质。此外,活性氧依赖性 STAT3 激活已被确定为血管平滑肌细胞中 PDGFR 信号传导的关键下游介质。

目录号 产品名/同用名 种属 表达系统
TMPK-00419 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) Human HEK293
TMPK-00420 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TMPK-00421 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) Human HEK293
TMPK-00422 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TMPK-00481 PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TMPK-01050 PDGF R beta/CD140b Protein, Canine, Recombinant (His) Canine HEK293
TMPY-00385 PDGFRB Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
TMPY-00900 PDGFRA Protein, Human, Recombinant (hFc) Human HEK293
TMPY-01207 PDGFRB Protein, Human, Recombinant (His) Human HEK293
TMPY-03140 PDGFRB Protein, Rat, Recombinant (His) Rat HEK293
TMPY-03474 PDGFRB Protein, Rat, Recombinant (hFc) Rat HEK293
TMPY-03590 PDGFRB Protein, Rhesus, Recombinant (His) Rhesus HEK293
TMPY-03825 PDGFRA Protein, Rat, Recombinant (His) Rat HEK293
TMPY-03919 PDGFRA Protein, Rat, Recombinant (hFc) Rat HEK293
TMPY-04937 PDGFRB Protein, Human, Recombinant (His), Biotinylated Human HEK293
TMPY-05358 PDGFRB Protein, Human, Recombinant Human HEK293
TMPY-05497 PDGFRB Protein, Human, Recombinant (hFc) Human HEK293
TMPY-05608 PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TMPY-05787 PDGFRA Protein, Mouse, Recombinant (His) Mouse HEK293
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