Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 2,960 | 5日内发货 | ||
500 μg | ¥ 11,800 | 5日内发货 | ||
1 mg | ¥ 19,700 | 5日内发货 |
生物活性 | Immobilized Cynomolgus PDGFR beta, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 8.3ng/ml determined by ELISA. |
产品描述 | Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target. |
种属 | Cynomolgus |
表达系统 | HEK293 |
标签 | C-His |
蛋白编号 | A0A2K5TUS0 |
别名 | PDGF R beta, PDGFRB, PDGFR-2, PDGF-R-β, PDGF-R-beta, PDGFR-β, PDGFR-beta, PDGF R β, PDGF R β/CD140b |
蛋白构建 | Recombinant Cynomolgus PDGF R beta/CD140b Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Leu33-Lys531.[Accession |A0A2K5TUS0] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 57.49 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target. |
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PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) PDGF R beta PDGFRB PDGFR-2 PDGF-R-β PDGF-R-beta PDGFR-β PDGFR2 PDGFR-b PDGFR-beta PDGF R β PDGFR 2 PDGF R β/CD140b recombinant recombinant-proteins proteins protein