T16375
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Octaethylene glycol
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Octaethylene glycol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T16208
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N-Boc-N-bis(PEG4-OH)
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N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
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T18526
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PDB-Pfp
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PDB-Pfp is a reducible ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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T14455
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Azido-PEG5-Ala-Ala-Asn-PAB
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Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
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T17547
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Biotin-C10-NHS Ester
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Biotin-C10-NHS Ester is an alkyl/ether-based linker compound utilized in the synthesis of PROTACs[1].
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T16191
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N-(Azido-PEG3)-N-Fluorescein-PEG3-acid
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N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEGylated PROTAC linker incorporating azide, fluorescein, and carboxylic acid functional groups.
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T17746
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DBCO-C3-PEG4-amine
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DBCO-C3-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14754
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Boc-NH-PEG7-acid
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Boc-NH-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18049
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Ibrutinib-biotin
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Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, has an IC50 of 0.755-1.02 nM for BTK.
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T15060
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DBCO-Maleimide
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DBCO-Maleimide is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs). [1]
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T14654
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Bis-propargyl-PEG12
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Bis-propargyl-PEG12 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18532
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PEG20-Tos
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PEG20-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T14660
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Bis-propargyl-PEG7
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Bis-propargyl-PEG7 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). It is particularly employed for the synthesis of polymer-linked multimers of guanosine-3',5'-cyclic monophosphates[1].
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T18124
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m-PEG11-azide
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m-PEG11-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T15330
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Fmoc-PEG3-C2-NHS ester
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Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based linker derived from fluorenylmethoxycarbonyl (Fmoc), which is used as a moiety for the efficient synthesis of PROTACs (proteolysis-targeting chimeras)[1]. This compound offers a practical solution for connecting desired molecules and targeting specific proteins for degradation.
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T15325
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Fmoc-NH-PEG9-CH2CH2COOH
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Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
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T15084
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Dde Biotin-PEG4-azide
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Dde Biotin-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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T18790
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Tetrazine-PEG4-oxyamine hydrochloride
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Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4-unit polyethylene glycol (PEG) linker, employed for the synthesis of antibody-drug conjugates (ADCs) [1].
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T17933
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endo-BCN-PEG12-NHS ester
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Endo-BCN-PEG12-NHS ester is a polyethylene glycol (PEG) derivative used as a linker for ProTAC synthesis [1].
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T18361
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MMAE-SMCC
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MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugates (ADC). It consists of MMAE, a potent inhibitor of mitosis and tubulin, and SMCC, a linker that facilitates the development of ADCs.
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