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Linker

产品编号 产品名称
T17883 Pomalidomide-PEG3-C2-NH2 Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 3 单元 PEG 的linker。
T17015L (S)-TCO-PEG4-acid (S)-TCO-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17853 DSPE-PEG-Maleimide (MW 5000) DSPE-PEG-Maleimide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16603 Propargyl-PEG2-OH Propargyl-PEG2-OH is a polyethylene glycol (PEG)-based PROTAC linker, specifically designed for efficient synthesis of Thalidomide-O-PEG2-propargyl.
T17670 Boc-NH-PEG15-azide Boc-NH-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17718 Cbz-NH-PEG10-CH2COOH Cbz-NH-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18325 MC-Val-Cit-PAB-Indibulin MC-Val-Cit-PAB-Indibulin is an antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), featuring the orally active tubulin assembly inhibitor, Indibulin, connected through the MC-Val-Cit-PAB ADC linker. This compound exhibits potent antitumor activity.
T14182 Alkyne-ethyl-PEG1-Boc Alkyne-ethyl-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15078 DBCO-Sulfo-NHS ester sodium DBCO-Sulfo-NHS ester sodium is a cleavable linker predominantly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T18349 Methyltetrazine-PEG4-NH-Boc Methyltetrazine-PEG4-NH-Boc is a PEGylation-based linker employed for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].
T18623 Boc-NH-PEG2-C2-amido-C4-acid Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T18164 m-PEG24-NHS ester m-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14771 Br-PEG4-C2-Boc Br-PEG4-C2-Boc is a cleavable 4-unit PEG ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
T15297 Fluorescein-thiourea-PEG2-azide Fluorescein-thiourea-PEG2-azide is a PEG-derived linker commonly applied for the synthesis of PROTACs[1].
T15873 m-PEG4-C6-phosphonic acid ethyl ester m-PEG4-C6-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based linker compound utilized for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
T17888 cIAP1 Ligand-Linker Conjugates 6 hydrochloride cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
T16637 Propargyl-PEG6-NHS ester Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
T14605 Biotin-PEG5-NH-Boc Biotin-PEG5-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18280 Mal-PEG24-acid Mal-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17322 1-(Isopropylthio)-2,3,4,6-tetra-o-Ac-beta-D-glucosylpyranose 1-(Isopropylthio)-2,3,4,6-tetra-o-Ac-beta-D-glucosylpyranose is an alkyl chain-derived PROTAC linker utilized in the synthesis of PROTACs[1].
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