T17883
|
Pomalidomide-PEG3-C2-NH2
|
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 3 单元 PEG 的linker。
|
T17582
|
DADPS Biotin Azide
|
DADPS Biotin Azide (Biotin-PEG4-amino-t-Bu-DADPS-C6-azide) 是一种属于 PEG 类的 PROTAC linker,可用于合成 PROTAC 分子。
|
T17015L
|
(S)-TCO-PEG4-acid
|
(S)-TCO-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T17853
|
DSPE-PEG-Maleimide (MW 5000)
|
DSPE-PEG-Maleimide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T16603
|
Propargyl-PEG2-OH
|
Propargyl-PEG2-OH is a polyethylene glycol (PEG)-based PROTAC linker, specifically designed for efficient synthesis of Thalidomide-O-PEG2-propargyl.
|
T17670
|
Boc-NH-PEG15-azide
|
Boc-NH-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T17718
|
Cbz-NH-PEG10-CH2COOH
|
Cbz-NH-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T18325
|
MC-Val-Cit-PAB-Indibulin
|
MC-Val-Cit-PAB-Indibulin is an antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), featuring the orally active tubulin assembly inhibitor, Indibulin, connected through the MC-Val-Cit-PAB ADC linker. This compound exhibits potent antitumor activity.
|
T14182
|
Alkyne-ethyl-PEG1-Boc
|
Alkyne-ethyl-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T15078
|
DBCO-Sulfo-NHS ester sodium
|
DBCO-Sulfo-NHS ester sodium is a cleavable linker predominantly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
|
T18349
|
Methyltetrazine-PEG4-NH-Boc
|
Methyltetrazine-PEG4-NH-Boc is a PEGylation-based linker employed for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].
|
T18623
|
Boc-NH-PEG2-C2-amido-C4-acid
|
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
|
T18164
|
m-PEG24-NHS ester
|
m-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T14771
|
Br-PEG4-C2-Boc
|
Br-PEG4-C2-Boc is a cleavable 4-unit PEG ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
|
T15297
|
Fluorescein-thiourea-PEG2-azide
|
Fluorescein-thiourea-PEG2-azide is a PEG-derived linker commonly applied for the synthesis of PROTACs[1].
|
T15873
|
m-PEG4-C6-phosphonic acid ethyl ester
|
m-PEG4-C6-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based linker compound utilized for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
|
T17888
|
cIAP1 Ligand-Linker Conjugates 6 hydrochloride
|
cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
|
T16637
|
Propargyl-PEG6-NHS ester
|
Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
|
T14605
|
Biotin-PEG5-NH-Boc
|
Biotin-PEG5-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|
T18280
|
Mal-PEG24-acid
|
Mal-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
|