T15732
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CDK
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Ribociclib succinate (LEE011 succinate) 是一种高度特异性的CDK4/6抑制剂,IC50值分别为 10 nM 和 39 nM。它对细胞周期蛋白 B/CDK1 复合物的效力低 1000 倍。 |
T15731
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CDK
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Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
T15730
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CDK
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Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
T6199
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VEGFR
CDK
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Ribociclib (LEE011) 是一种细胞周期蛋白依赖性激酶 CDK4/6 抑制剂 (IC50=10/39 nM),具有特异性和口服活性。Ribociclib 具有抗肿瘤活性,可以阻滞细胞周期,抑制肿瘤细胞增殖。 |