TN6519
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Saucerneol
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Saucerneol has significant cardiovascular effects such as vasorelaxant and negative inotropic actions.
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TN4489
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Manassantin A
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Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB act
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TN4490
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Manassantin B
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Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.
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TN1581
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Dihydroguaiaretic acid
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Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
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T10017
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1-Linoleoyl Glycerol
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1-Linoleoyl Glycerol (Monolinolein) 是脂肪酸甘油。
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T7781
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Reynoutrin
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Reynoutrin (Reinutrin) 是一种黄酮类化合物,从草莓番石榴中得到,具有抗氧化清除自由基的活性。
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T6S1572
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Sauchinone
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Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS,TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
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