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TCS2336
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Evodine
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Evodine 是吴茱萸中的主要柠檬苦素，是P-gp 有效抑制剂，可通过保留抗氧化剂防御系统，针对谷氨酸诱导的毒性具有保护作用。
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TN1175
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1-Methyl-2-pentyl-4(1H)-quinolinone
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1-Methyl-2-pentyl-4(1H)-quinolinone is a natural product
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TN2553
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1-Methyl-2-undecyl-4(1H)-quinolone
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1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells.
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TN6057
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1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone
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(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria.
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TN5067
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Stigmastane-3,5,6-triol
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Stigmastane-3,5,6-triol and derivatives could be used for preparing antiviral medicine.
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TN1173
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1-Hydroxyrutaecarpine
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1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro.
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TN2604
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12alpha-Hydroxyevodol
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12alpha-Hydroxyevodol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2604，CAS号为 120722-04-5。
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TN4440
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Limonexic acid
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Limonexic acid shows antinociceptive actions , it produces dose-related inhibition of glutamate- and capsaicin-induced pain. Limonexic acid can effectively protect hepatocyte against CCl4-induced injury.
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TN2673
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5-Methoxy-2',3'-dehydromarmesin
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5-Methoxy-2',3'-dehydromarmesin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2673，CAS号为 54087-32-0。
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TN4061
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Flavaprin
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Flavaprin是一种天然产物，属于芸香科三桠苦属，其产品编号为 TN4061，CAS号为 53846-49-4。Flavaprin可用作对照参考。
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TN1752
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Hydroxyevodiamine
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Hydroxyevodiamine is a natural product
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TN1638
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Evodol
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Evodol may as an anti-inflammatory agent or lead compound, it shows inhibitory activity on nitric oxide (NO) production in lipopolysaccharide -activated RAW264.7 macrophages. Evodol and limonin possess larvicidal activity against the Asian tiger mosquitoe
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TN2681
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Elasticamide
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(2S,3S,4R,2'R)-2-(2'-hydroxytetracosanoylamino)octadecane-1,3,4-triol shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom at concentration of 100 ug/mL.
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TN4135
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Glaucin B
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Glaucin B is a new bitter limonoid.
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TN1099
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Dihydroevocarpine
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Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a moderate modulator of p-glycoprotein (p-gp) activity; it shows more potent inhibitory effects against MAO-B compared to MAO-A.
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TN3237
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7-Isopentenyloxy-gamma-fagarine
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7-Isopentenyloxy-gamma-fagarine has highly cytotoxicity against the MCF-7and Jurkat cell line. It has been used as a precursor for the chemical asymmetric synthesis of the enantiopure alkaloids: evoxine, anhydroevoxine and evodine.
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TN4044
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Evodosin A
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Evodosin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4044，CAS号为 1291053-38-7。
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TN3151
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6-Acetonyl-N-methyl-dihydrodecarine
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6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae.
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TN2552
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1-Methyl-2-nonylquinolin-4(1H)-one
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1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM.
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T2S2335
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Dehydroevodiamine
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Dehydroevodiamine (DHED) 是从吴茱萸中分离出的一种喹唑啉生物碱，可抑制 LPS 诱导的小鼠巨噬细胞中iNOS、COX-2、PGE2和NF-κB 的表达，对豚鼠心室肌细胞具有抗心律失常作用。
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