醌类化合物是中药中一类具有醌式结构的化学成分,主要分为苯醌、萘醌、菲醌和蒽醌四种类型。醌类化合物是许多天然药物如大黄、何首乌、虎杖、决明子、芦荟、丹参等药材的有效成分。醌类化合物具有多方面的生理活性,如致泻、抗菌、利尿和止血等,还有一些醌类化合物具有抗癌、抗病毒、解痉平喘等作用,是一类很有前途的天然产物。
产品编号 | 产品名称 | ||
---|---|---|---|
TN2375 | Isoeleutherin | Isoeleutherin Has anti-cancer and anti-inflammatory effects. | |
T2723 | Ketoisophorone | Ketoisophorone is the major ingredients of saffron spice. It is a cyclic olefin and was reported as a product of the thermal degradation of β-carotene in aqueo... | |
T3827 | Rhein-8-glucoside calcium | Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |
T4241 | Rubiadin | Rubiadin possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner. | |
T0800 | Danthron | Danthron is a natural product, regulates glucose, and lipid metabolism by activating AMPK. | |
TN1491 | Chrysophanol tetraglucoside | Chrysophanol 1-O-beta-tetraglucoside is a natural product | |
T5780 | HYPOCRELLIN B | HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer c... | |
TN1414 | Aurantio-obtusin β-D-glucoside | Aurantio-obtusin beta-D-glucoside is a natural product | |
TN2163 | Rubioncolin C | Rubioncolin C shows good cytotoxicity with IC50 value of 1.53 μM and NF-κB inhibitory activity with IC50 value of 2.97 μM. | |
T3S0381 | Chrysophanol 8-O-glucoside | Chrysophanol 8-O-glucoside and chrysophanol have mild cytotoxicity and anti-diabetic properties and can play metabolic roles in the insulin-stimulated glucose tr... | |
T1273 | Diacerein | Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is res... | |
TN1467 | Carmine | Carmine is used in the manufacture of artificial flowers, paints, crimson ink, rouge, and other cosmetics, and is routinely added to food products such as yogurt... | |
TN1756 | Hypocrellin C | Standard reference | |
TN2101 | Primin | Primin has antimycobacterial, and strong antineoplastic actions. | |
TN1211 | 2-Hydroxy-3-methylanthraquinone | 2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activ... | |
TN1213 | 2-(Hydroxymethyl)anthraquinone | 2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. | |
TN1208 | 2-Amino-3-carboxy-1,4-naphthoquinone | 2-Amino-3-carboxy-1,4-naphthoquinone is a novel growth stimulator for bifidobacteria, it affects the end-product profile of bifidobacteria through the mediated o... | |
TN2164 | Rubipodanone A | Rubipodanone A is a natural product | |
TN1885 | Lucidin 3-O-glucoside | Lucidin 3-O-glucoside is a natural product | |
TN2064 | Physcion 8-O-β-D-glucopyranoside | Physcion 8-O-beta-D-monoglucoside has anti-inflammatory activity, it can inhibit TNF-α±-induced cytotoxicity and apoptosis in L929 cells via TNF-R1. | |
T3008 | Lawsone methyl ether | Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well a... | |
T5S2343 | Acetyl shikonin | 1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and a... | |
T3S2344 | β,β-Dimethylacrylshikonin | 1. Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combine... | |
TN1017 | Physion 8-O-β-D-glucoside | Physcion 1-O-beta-D-glucoside is a tumor cell growth inhibitor. | |
T5S1177 | Aloin B | 1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the res... | |
TN1886 | Lucidin primeveroside | Lucidin-3-O- primeveroside, a food pigment, shows effective antifeedant against the carpet beetle. It is reported to be carcinogenic in the kidney and liver of r... | |
T2796 | Coenzyme Q10 | Coenzyme Q10 (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain. | |
TN1053 | Aloe-emodin-8-O-β-D-glucopyranoside | Aloe-emodin-8-O-beta-D-glucopyranoside shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |
TN2154 | Rhein 8-Glucoside | Rhein-8-glucoside has low laxative activity. | |
T5703 | β,β-Dimethylacrylalkannin | β,β-Dimethylacrylalkannin is a natural product isolated from Arnebia nobilis Reichb.f, increases collagen and involucrin content in skin cells. | |
TN1569 | Deoxylapachol | Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white ... | |
TN2131 | Questin | Questin has promising inhibitory potential against AChE, BChE, and BACE1, it may be used in the development of therapeutic or preventive agents for Alzheimer's d... | |
T5S2347 | Deoxyshikonin | 1. Deoxyshikonin may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphat... | |
TN1375 | α-Lapachone | alpha-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi. | |
TN1549 | Damnacanthal | Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its... | |
T4S0969 | Obtusifolin | 1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin supp... | |
T2997 | Rhein | Rhein is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities. | |
TN2339 | Eleutherol | Eleutherol Derived from Eleutherine plicata. | |
T4010 | Juglone | Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl... | |
T2841 | Plumbagin | Plumbagin is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also co... | |
T2843 | Aloe emodin | Aloe-emodin is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ). | |
TN1504 | Citreorosein | Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both... | |
TN1492 | Chrysophanein | Chrysophanol 1-O-glucoside is a natural product | |
TN1371 | Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside | Aloe-emodin-3-(hydroxymethyl)-O-beta-D-glucopyranoside is a natural product | |
T4586 | (Rac)-Arnebin 1 | beta, beta-dimethylacrylshikonin has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver. | |
TN1034 | Sennidin B | Sennidin B stimulates glucose incorporation in rat adipocytes. | |
T4958 | (-)-Alkannin | Shikonin is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used fo... | |
T2869 | Emodin | Emodin is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated b... | |
TN2315 | Xanthopurpurin | Xanthopurpurin shows antiviral activity, it can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin... | |
T3019 | Physcion | Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenas... | |
TN1649 | Frangulin A | Frangulin A is a natural product | |
TN1137 | Isobutylshikonin | Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·... | |
TN2109 | Protopseudohypericin | Protopseudohypericin is a natural product | |
TN2108 | Protohypericin | Protohypericin exhibits photocytotoxicity. | |
T6S0923 | Hypericin | 1. Hypericin has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoa... | |
T6485 | Embelin | Embelin, isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM). | |
TN2115 | Pseudohypericin | Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS. | |
T0449 | Menadione | Menadione is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after ... | |
TN1618 | Erigeroside | Erigeroside has the protective effects on cerebral ischemia-reperfusion injury in rat, its ability of anti-oxidation and scavenging oxidation free radical may be... | |
TN1582 | Dihydromollugin | Dihydromollugin is a natural product | |
TN1209 | 2-Hydroxy-1-methoxyanthraquinone | 2-Hydroxy-1-methoxy- anthraquinone has antiosteoporotic activity, it can promote osteoblast proliferation, and can inhibit osteoclast TRAP activity and bone reso... | |
TN1172 | 1-Hydroxy-2-methylanthraquinone | 1-Hydroxy-2-methylanthraquinone exhibits promising larvicidal activity. | |
TN1033 | Sennidin A | Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM. | |
T6S1559 | Aurantio-obtusin | 1. Biotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation... | |
T5S2350 | Beta-Acetoxyisovalerylshikonin | ||
TN2004 | Obtusin | Obtusin is a natural product | |
T2949 | Alizarin | Alizarin, a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 μM), CYP1A2 (IC50 =10.0 μM )and CYP1B1(IC50 ... | |
TN1440 | Beta-Hydroxyisovalerylshikonin | Beta-Hydroxyisovalerylshikonin is an ATP non-competitive inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in ... | |
T7050 | Alpha-Tocopherolquinone | During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has al... | |
T5771 | Hypocrellin A | Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presen... | |
T5680 | ALOIN | ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells. | |
TN1253 | 3-hydroxymorindone | 3-hydroxymorindone is a natural product | |
T5648 | Purpurin | Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative ... | |
TN2132 | Quinizarin | Quinizarin is a natural product | |
T2969 | Lawsone | Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well a... | |
TN2261 | Tectoquinone | Tectoquinone exhibits strong mosquito larvicidal activity. | |
T4136 | Lapachol | Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tum... | |
T1075 | Vitamin K1 | Vitamin K1 a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity. | |
TN1604 | Emodin-1-O-β-gentiobioside | Emodin-1-O-beta-gentiobioside is a natural product | |
TN1400 | Aristolindiquinone | Aristolindiquinone is a natural product | |
TN1316 | 6-Hydroxyrubiadin | 6-Hydroxyrubiadin has antioxidant activity, EC(50) is 14.7ug/ml. | |
TN1167 | 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl-(1→2)-β-D-glucoside | 1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside shows certain antibacterial activity. | |
TN1168 | 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone 3-O-α-rhamnosyl-(1→2)-β-glucoside | 1,3,6-Trihydroxy-2-methylanthraquinone 3-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside is a natural product |