抗癌活性化合物库

Anti-cancer Active Compound library
产品编号 L2160
  库化合物信息   Excel SDF

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功,但癌症仍然是人类面临的巨大挑战,给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征,表现出无限的增殖潜能,维持自身生长信号的持续稳定,逃避应激信号诱导的细胞凋亡,刺激血管生长,为肿瘤提供营养,同时逃避免疫系统防御和诱导局部慢性炎症,发挥其侵袭和转移能力;并且表现出异常的代谢活动,并通过突变和表观遗传机制显著改变全基因组的稳定性。

根据文献报道和有关公开资料,我们挑选了1656个具有已知抗癌活性的化合物组成抗癌活性库,可用于具体癌症的阳性对照及癌症机理的研究。希望我们在抗癌研究的路上,助您一臂之力!

抗癌活性化合物库
规格 价格/RMB
100 μL * 10 mM (in DMSO) 161456.00
250 μL * 10 mM (in DMSO) 264960.00
1 mg 264960.00
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产品描述

  • 1656种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
  • 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具;
  • 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS检测技术保证产品高纯度和高质量,减少假阳性发生概率。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L2160)

化合物库组成

VEGFR (64)
PI3K (60)
EGFR (55)
CDK (52)
DNA/RNA Synthesis (45)
FGFR (41)
PDGFR (40)
Bcr-Abl (37)
c-Kit (36)
FLT (36)
mTOR (35)
c-Met/HGFR (34)
HDAC (33)
Topoisomerase (30)
Src (30)
JAK (27)
Microtubule Associated (27)
NF-κB (25)
Raf (25)
Estrogen/progestogen Receptor (24)
Apoptosis (23)
Akt (22)
HSP (22)
STAT (22)
ALK (21)
Autophagy (21)
MEK (20)
Epigenetic Reader Domain (20)
DNA-PK (19)
TNF (19)
PKC (19)
Tyrosine Kinases (18)
Dehydrogenase (17)
Aurora Kinase (17)
DNA Alkylation (16)
BCL (16)
TAM Receptor (16)
COX (15)
c-RET (15)
HER (15)
Endogenous Metabolite (14)
Androgen Receptor (13)
PARP (13)
P450 (12)
FAK (12)
ERK (12)
IGF-1R (12)
HIF (11)
ATM/ATR (11)
p38 MAPK (11)
Mdm2 (11)
PPAR (10)
Retinoid Receptor (10)
S6 Kinase (10)
Wnt/beta-catenin (10)
Caspase (10)
BTK (10)
IL Receptor (10)
Histone Methyltransferase (10)
Hedgehog/Smoothened (9)
Chk (9)
Trk receptor (9)
TGF-beta/Smad (9)
PLK (9)
Proteasome (9)
p53 (9)
Antioxidant (8)
Antiviral (8)
AChR (8)
GSK-3 (8)
HIV Protease (8)
GR (7)
MAO (7)
MMP (7)
IDO (7)
Histamine Receptor (7)
Glucocorticoid Receptor (7)
Adrenergic Receptor (7)
Antibacterial (7)
Calcium Channel (7)
CSF-1R (7)
CXCR (7)
c-Fms (6)
Antibiotic (6)
Apoptosis inducer (6)
Aromatase (6)
Gamma-secretase (6)
Histone Demethylase (6)
P-gp (6)
Pim (6)
Potassium Channel (6)
ROS (6)
TLR (6)
Vitamin (6)
Sodium Channel (5)
PDE (5)
Ras (5)
PKA (5)
PDK (5)
NOS (5)
GABA Receptor (5)
IκB/IKK (5)
Lipoxygenase (5)
IAP (5)
Integrin (5)
JNK (5)
Antifungal (5)
AMPK (5)
Adenosine Receptor (5)
CaMK (5)
Dopamine Receptor (5)
Cysteine Protease (4)
CCR (4)
Casein Kinase (4)
Antifection (4)
ATPase (4)
MAPK (4)
HBV (4)
Glucokinase (4)
DUB (4)
Phosphatase (4)
Phospholipase (4)
ROCK (4)
Serine Protease (4)
Sirtuin (4)
Transferase (4)
transporter (4)
UGT (3)
Tyrosinase (3)
Survivin (3)
Syk (3)
Tie-2 (3)
S1P Receptor (3)
Rho (3)
PYK2 (3)
Prostaglandin Receptor (3)
PAK (3)
Opioid Receptor (3)
NAMPT (3)
Monocarboxylate transporter (3)
E1/E2/E3 Enzyme (3)
Ephrin Receptor (3)
Fatty Acid Synthase (3)
GNRH Receptor (3)
Liver X Receptor (3)
LPA Receptor (3)
lysosomal autophagy (3)
Kinesin (3)
Annexin A (3)
Aminopeptidase (3)
5-HT Receptor (3)
cell cycle arrest (3)
Beta Amyloid (3)
DHFR (3)
cholecystokinin (3)
DNA Methyltransferase (3)
DNA Alkylator/Crosslinker (2)
Carbonic Anhydrase (2)
Chloride channel (2)
c-Myc (2)
AhR (2)
Amino Acids and Derivatives (2)
ATP Citrate Lyase (2)
BCRP (2)
KSP (2)
HSV (2)
Hydroxylase (2)
Mitophagy (2)
GPX (2)
GTPase (2)
Hexokinase (2)
MRP (2)
NADPH (2)
OXPHOS (2)
NMDAR (2)
NOD (2)
p97 (2)
Reactive Oxygen Species (2)
Reductase (2)
ROR (2)
TOPK (2)
STING (2)
Wee1 (2)
VDA (1)
TRP/TRPV Channel (1)
Xanthine Oxidase (1)
Smo (1)
Stemness kinase (1)
Thioredoxin (1)
Thrombin (1)
Telomerase (1)
ribosome (1)
Reverse Transcriptase (1)
Serine/threonin kinase (1)
Serotonin Transporter (1)
SGK (1)
SGLT (1)
Sigma receptor (1)
SIK (1)
RAAS (1)
PTEN (1)
Protease-activated Receptor (1)
Porcupine (1)
PKM (1)
PAFR (1)
Parasite (1)
PD-1/PD-L1 (1)
PI4K (1)
Nrf2 (1)
Nucleoside Antimetabolite/Analog (1)
MTH1 (1)
MPO (1)
HIF/HIF Prolyl-Hydroxylase (1)
Hck (1)
HCV Protease (1)
GPCR19 (1)
GPR (1)
Ferroptosis (1)
GluR (1)
GHSR (1)
Estrogen Receptor/ERR (1)
Free radical scavengers (1)
MNK (1)
Melatonin Receptor (1)
MELK (1)
MALT (1)
LTR (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
Influenza Virus (1)
LHRH (1)
Lipase (1)
IRAK (1)
Isocitrate Dehydrogenase (IDH) (1)
ASK (1)
Antifolate (1)
Adiponectin receptor (1)
ABC (1)
AChE (1)
ACK (1)
DPP-4 (1)
Discoidin Domain Receptor (DDR) (1)
Dehydrogenase inhibitor (1)
Deubiquitinase (1)
CRM1 (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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