抗胰腺癌化合物库

Anti-Pancreatic Cancer Compound Library
产品编号 L2192
  库化合物信息   Excel SDF

随着医学技术的进步,大部分癌症的生存率都在提高,例如乳腺癌,结直肠癌等肿瘤,近几十年来,生存率得到了大幅度的提升。但是,有一个例外,那就是胰腺癌,胰腺癌是一种发病隐匿,进展迅速,治疗效果和预后极差的消化道恶性肿瘤。胰腺癌的生存率一直停滞不前,胰腺癌的五年生存率只有5%至10%,绝大部分患者在诊断胰腺癌半年内死亡,由于生存率低,死亡率高,胰腺癌称为癌中之王。

为了满足胰腺癌研究客户的需求,TargeMol 收集了1697种与胰腺癌相关的化合物,作用于KRas, MEK, ERK, RAF, PI3K, HER2, EGFR, JAK/STAT, IGF-1R, VEGF, TGFβ等胰腺癌相关靶点,助力胰腺癌治疗药物的开发。

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
抗胰腺癌化合物库
规格
30 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
1 mg
咨询化合物库

产品特点

  • 1697种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选;
  • 靶点含KRas, MEK, ERK, RAF, PI3K, HER2, EGFR, JAK/STAT, IGF-1R, VEGF, TGFβ等;
  • 部分化合物已上市或已进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L2192)

化合物库组成

PI3K (111)
EGFR (108)
VEGFR (106)
NF-κB (98)
JAK (66)
PDGFR (62)
FGFR (60)
mTOR (57)
ERK (53)
Raf (51)
p38 MAPK (49)
STAT (48)
Akt (45)
c-Kit (42)
Src (38)
AMPK (35)
GSK-3 (35)
MMP (33)
MEK (32)
FLT (32)
CDK (31)
TGF-beta/Smad (31)
Tyrosine Kinases (27)
DNA-PK (27)
JNK (26)
HIF (24)
HER (23)
p53 (23)
Bcr-Abl (22)
S6 Kinase (22)
ATM/ATR (20)
c-Met/HGFR (20)
Hedgehog/Smoothened (20)
MAPK (19)
TNF (18)
IGF-1R (17)
Autophagy (17)
c-RET (15)
COX (14)
Ras (14)
PKC (14)
Aurora Kinase (13)
Apoptosis (11)
Potassium Channel (10)
HIF/HIF Prolyl-Hydroxylase (10)
DNA/RNA Synthesis (10)
IL Receptor (9)
Pim (9)
Trk receptor (9)
PKA (8)
PDK (8)
PERK (8)
ALK (8)
Casein Kinase (8)
Caspase (8)
BCL (7)
c-Fms (7)
Chk (7)
PPAR (7)
HDAC (7)
MLK (6)
FAK (6)
Adrenergic Receptor (6)
BTK (6)
ROCK (6)
Syk (6)
TAM Receptor (6)
Tie-2 (5)
CSF-1R (5)
Dehydrogenase (5)
Mdm2 (5)
Microtubule Associated (5)
Lipoxygenase (4)
IκB/IKK (4)
MNK (4)
PDE (4)
P450 (4)
Beta Amyloid (4)
Antibacterial (4)
AChR (4)
Antioxidant (4)
ROS (4)
PLK (4)
Serine Protease (3)
SGK (3)
Sodium Channel (3)
Wnt/beta-catenin (3)
Tyrosinase (3)
5-HT Receptor (3)
Calcium Channel (3)
ATPase (3)
BACE (3)
Carbonic Anhydrase (3)
cholecystokinin (3)
Endogenous Metabolite (3)
Ephrin Receptor (3)
Epigenetic Reader Domain (3)
NOS (3)
PARP (3)
NADPH (3)
Integrin (3)
Hck (3)
HSP (3)
HSV (3)
Immunology & Inflammation related (2)
MELK (2)
LRRK2 (2)
LDL (2)
MPO (2)
Nrf2 (2)
PI4K (2)
DNA Alkylation (2)
Estrogen/progestogen Receptor (2)
Glucokinase (2)
Discoidin Domain Receptor (DDR) (2)
Cysteine Protease (2)
Antiviral (2)
Antifection (2)
Somatostatin (2)
SIK (2)
Sirtuin (2)
S1P Receptor (2)
TOPK (2)
Topoisomerase (2)
transporter (2)
TRP/TRPV Channel (1)
UGT (1)
Vitamin (1)
Transferase (1)
TLR (1)
Thioredoxin (1)
Serine/threonin kinase (1)
Salt-Inducible Kinase (1)
Survivin (1)
YAP (1)
Antifungal (1)
Apoptosis inducer (1)
Aromatase (1)
ASK (1)
ABC (1)
ACK (1)
Antibiotic (1)
ATP Citrate Lyase (1)
CaMK (1)
Cannabinoid Receptor (1)
CCR (1)
DNA (1)
Dopamine Receptor (1)
DPP-4 (1)
E1/E2/E3 Enzyme (1)
c-Myc (1)
Chloride channel (1)
CFTR (1)
GluR (1)
Fatty Acid Synthase (1)
Free radical scavengers (1)
GABA Receptor (1)
Gamma-secretase (1)
Gap Junction Protein (1)
FAAH (1)
P-gp (1)
Phosphatase (1)
Prostaglandin Receptor (1)
PTEN (1)
PYK2 (1)
Retinoid Receptor (1)
Reverse Transcriptase (1)
PAFR (1)
PAI-1 (1)
NOD (1)
Lipase (1)
LTR (1)
lysosomal autophagy (1)
Mitophagy (1)
IRAK (1)
Hippo pathway (1)
Histamine Receptor (1)
Histone Methyltransferase (1)
HIV Protease (1)
hCE (1)
Hexokinase (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat Fasiglifam TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS-754807 Enmetazobactam
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG-208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol TRIA-662 MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv 3-Pyridinemethanol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 BMP signaling agonist sb4 Daclatasvir Daclatasvir dihydrochloride NADPH tetracyclohexanamine AZD-8055 Vistusertib PAβN dihydrochloride HZ-1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin-3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A 78U Tenovin-6 Normetanephrine hydrochloride Triclocarban CUDC-101 Chlorpropham Pyridostigmine bromide Zacopride hydrochloride PF-04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine dihydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
陶术生物的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务,也不为任何个人提供产品和服务。陶素|陶素生化|陶术|陶术生物
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