Ro5类药天然产物库 | 陶术生物

Ro5类药天然产物库现货

RO5 Drug-like Natural Product Library

产品编号： L6160

天然产物是先导化合物及候选药物的重要来源，其骨架结构复杂，官能团丰富，结构独特，多具有手性。这些自然形成的优势，为天然产物向药物的转化提供了更加多样的选择, 也是天然产物在药物开发与研究中发挥着重要作用的原因。

TargetMol 应用类药性评价指标“Lipinski 五规则”，基于天然产物结构的多样性和新颖性，优选出符合 RO5原则的 2743 个成药性良好的天然产物单体，涵盖萜类，生物碱类等多种结构类型，兼具生物活性和类药性，是新药发现、药物筛选和创新药物研究的有力工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

2743种符合“Lipinski 五规则”的天然产物集合，成药潜力高；
大部分化合物生物活性明确，具有抗肿瘤、抗炎、抗氧化、神经保护等多种功能；
结构多样，包含黄酮、皂苷、萜类、生物碱等类别；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

Endogenous Metabolite (803)

Apoptosis (258)

Antibacterial (218)

Autophagy (170)

NF-κB (112)

Antifungal (102)

Antibiotic (85)

Reactive Oxygen Species (74)

Parasite (66)

Antioxidant (61)

COX (61)

AChR (53)

P450 (52)

Influenza Virus (44)

Anti-infection (43)

DNA/RNA Synthesis (42)

AChE (38)

TNF (38)

GABA Receptor (35)

p38 MAPK (35)

5-HT Receptor (32)

IL Receptor (32)

Calcium Channel (31)

Caspase (31)

ERK (31)

Tyrosinase (31)

Akt (29)

Ferroptosis (29)

HIV Protease (29)

STAT (29)

NO Synthase (28)

Estrogen/progestogen Receptor (27)

Adrenergic Receptor (26)

Topoisomerase (26)

AMPK (24)

Nrf2 (24)

Virus Protease (24)

TRP/TRPV Channel (22)

MMP (21)

PI3K (21)

PPAR (21)

ROS (21)

Dopamine Receptor (20)

Estrogen Receptor/ERR (20)

Lipoxygenase (20)

BCL (19)

NOS (19)

Antifection (18)

PDE (18)

Potassium Channel (18)

PKC (17)

Dehydrogenase (16)

HSV (16)

JNK (16)

Microtubule Associated (16)

PARP (16)

EGFR (15)

Nucleoside Antimetabolite/Analog (15)

iGluR (14)

Mitophagy (14)

Adenosine Receptor (13)

Drug Metabolite (13)

Glucosidase (13)

HDAC (13)

Histamine Receptor (13)

Prostaglandin Receptor (13)

Amino Acids and Derivatives (12)

Antiviral (12)

HIF/HIF Prolyl-Hydroxylase (12)

Mitochondrial Metabolism (12)

Sodium Channel (12)

VEGFR (12)

Androgen Receptor (11)

GluR (11)

MAO (11)

P-gp (11)

Wnt/beta-catenin (11)

ATPase (10)

Glucocorticoid Receptor (10)

Immunology/Inflammation related (10)

JAK (10)

NMDAR (10)

CDK (9)

HBV (9)

Monoamine Oxidase (9)

SARS-CoV (9)

Sirtuin (9)

Opioid Receptor (8)

HCV Protease (7)

NOD (7)

Phospholipase (7)

Progesterone Receptor (7)

TGF-beta/Smad (7)

TLR (7)

Beta Amyloid (6)

Cannabinoid Receptor (6)

Chloride channel (6)

Fatty Acid Synthase (6)

GPR (6)

HER (6)

HIF (6)

HMG-CoA Reductase (6)

Indoleamine 2,3-Dioxygenase (IDO) (6)

Interleukin (6)

IκB/IKK (6)

MAPK (6)

mTOR (6)

PKA (6)

AhR (5)

Aryl Hydrocarbon Receptor (5)

BACE (5)

Carbonic Anhydrase (5)

FXR (5)

Gamma-secretase (5)

HSP (5)

NADPH (5)

PAFR (5)

Phosphatase (5)

Platelet aggregation (5)

Reductase (5)

Reverse Transcriptase (5)

Src (5)

Transferase (5)

transporter (5)

Xanthine Oxidase (5)

Arginase (4)

ATP Citrate Lyase (4)

CaMK (4)

cAMP (4)

c-Met/HGFR (4)

DNA Methyltransferase (4)

FGFR (4)

LDL (4)

MEK (4)

p53 (4)

PGE Synthase (4)

ribosome (4)

Serine/threonin kinase (4)

Syk (4)

UGT (4)

Aromatase (3)

Beta-Secretase (3)

CCR (3)

DHFR (3)

DNA (3)

Epigenetic Reader Domain (3)

FAK (3)

Free radical scavengers (3)

Glutathione Peroxidase (3)

GPCR19 (3)

GSK-3 (3)

GST (3)

Hedgehog/Smoothened (3)

IAP (3)

Imidazoline Receptor (3)

Integrin (3)

Lipid (3)

MRP (3)

Proton pump (3)

ROR (3)

Serotonin Transporter (3)

Telomerase (3)

Thyroid hormone receptor(THR) (3)

Trk receptor (3)

Tyrosine Kinases (3)

Aminopeptidase (2)

ATM/ATR (2)

Aurora Kinase (2)

Casein Kinase (2)

c-Myc (2)

CXCR (2)

Cysteine Protease (2)

Decarboxylase (2)

DNA Alkylator/Crosslinker (2)

DNA gyrase (2)

DPP-4 (2)

DYRK (2)

E1/E2/E3 Enzyme (2)

FAAH (2)

gp120/CD4 (2)

Histone Acetyltransferase (2)

IGF-1R (2)

LTR (2)

NOD-like Receptor (NLR) (2)

OAT (2)

PAI-1 (2)

PAK (2)

PDGFR (2)

PDK (2)

Phosphorylase (2)

PKM (2)

Proteasome (2)

RAAS (2)

RANKL/RANK (2)

Ras (2)

S6 Kinase (2)

Serine Protease (2)

Smo (2)

Thrombin (2)

ABC (1)

aconitase (1)

Acyltransferase (1)

Adenylyl cyclase (1)

Adiponectin receptor (1)

advanced glycation end products (1)

ALK (1)

Antifolate (1)

ATTECs (1)

BCRP (1)

Carboxypeptidase (1)

CAT (1)

CD38 (1)

CFTR (1)

CRISPR/Cas9 (1)

CYP19A1 (1)

DNA Alkylation (1)

Factor Xa (1)

FLT (1)

GlyT (1)

hCE (1)

Hexokinase (1)

Hydrogenase (1)

Hydroxylase (1)

IDO (1)

IRAK (1)

IRE1 (1)

Leukotriene Receptor (1)

Liver X Receptor (1)

LPL Receptor (1)

Mdm2 (1)

Melatonin Receptor (1)

Monoamine Transporter (1)

Monocarboxylate transporter (1)

MT Receptor (1)

NADPH-oxidase (1)

Neurokinin receptor (1)

NMU2R (1)

Norepinephrine (1)

OCT (1)

P2X Receptor (1)

P2Y Receptor (1)

PAD (1)

PD-1/PD-L1 (1)

Pim (1)

PLK (1)

Prolyl Endopeptidase (PREP) (1)

Pyroptosis (1)

Raf (1)

RAR/RXR (1)

Retinoid Receptor (1)

ROS Kinase (1)

S1P Receptor (1)

SGLT (1)

Somatostatin (1)

Stearoyl-CoA Desaturase (SCD) (1)

Transaminase (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

注册成功