自噬库 | 陶术生物

Autophagy Compound Library

产品编号： L3200

自噬是一个涉及到细胞自身物质或结构被溶酶体或液泡分解的过程。先是内质网脱落的双层膜包裹细胞内部分受损或老化的细胞器、蛋白质等成分形成自噬体，后与溶酶体或液泡融合降解其所包裹的内容物，以实现细胞本身的代谢需要和某些细胞器的更新。细胞自噬与细胞凋亡、细胞衰老一样，是十分重要的生物学现象，参与生物的发育、生长等多种过程，细胞自噬的异常导致癌细胞的出现。

TargetMol 自噬库集合了文献报道的 1248 种细胞自噬相关的生物活性小分子化合物，可用于细胞自噬机理研究和靶向药物筛选。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

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产品描述

1248种细胞自噬相关的生物活性小分子化合物的特有集合，用于自噬相关的研究，用于高通量、高内涵筛选 ;
产品经过临床验证和临床实验，具有生物安全保障和一定的生物活性 ;
是研究细胞自噬的机理以及药物靶向研究的有效工具 ;
活性包括自噬诱导、自噬抑制、蛋白酶体、HIF、E3 Ligase、mTOR等 ;
结构多样，药效显著，可渗透细胞 ;
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等 ;
NMR和HPLC检测技术保证产品高纯度和高质量 ;
所有化合物现货供应。

化合物库定制

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化合物库组成

Autophagy (824)

Apoptosis (333)

PI3K (99)

Antibacterial (92)

mTOR (72)

Endogenous Metabolite (67)

Antibiotic (65)

Mitophagy (54)

AMPK (46)

p38 MAPK (41)

HIV Protease (40)

Ferroptosis (39)

Akt (39)

HDAC (39)

NF-κB (39)

Parasite (34)

Reactive Oxygen Species (34)

CXCR (31)

Raf (30)

Calcium Channel (27)

Potassium Channel (27)

VEGFR (26)

Adrenergic Receptor (24)

CDK (23)

Aurora Kinase (23)

COX (23)

Retinoid Receptor (23)

DNA-PK (22)

ERK (22)

EGFR (22)

MEK (22)

p53 (22)

DNA/RNA Synthesis (21)

Bcr-Abl (20)

Influenza Virus (20)

P450 (20)

FLT (20)

c-Kit (20)

PDGFR (19)

Src (17)

PKC (17)

Topoisomerase (17)

LRRK2 (17)

5-HT Receptor (17)

AChR (17)

Antifungal (16)

GSK-3 (16)

Virus Protease (16)

CFTR (16)

PKA (15)

CaMK (15)

SARS-CoV (15)

Proteasome (14)

JNK (14)

BCL (14)

FGFR (14)

FXR (13)

E1/E2/E3 Enzyme (13)

FAAH (13)

TNF (13)

HMG-CoA Reductase (13)

S6 Kinase (13)

JAK (12)

Sirtuin (12)

STAT (12)

Sodium Channel (12)

Ras (12)

Microtubule Associated (12)

Dopamine Receptor (11)

Estrogen/progestogen Receptor (11)

PPAR (11)

PDE (11)

HSV (11)

MMP (11)

HIF/HIF Prolyl-Hydroxylase (11)

PERK (10)

Serine/threonin kinase (10)

Caspase (10)

Epigenetic Reader Domain (10)

DUB (10)

TLR (10)

Nrf2 (10)

ATM/ATR (10)

c-RET (10)

Mdm2 (9)

Dehydrogenase (9)

Mitochondrial Metabolism (9)

TGF-beta/Smad (9)

Casein Kinase (9)

Antioxidant (8)

Phosphatase (8)

PARP (8)

Nucleoside Antimetabolite/Analog (8)

TRP/TRPV Channel (8)

ROCK (8)

HIF (8)

ATPase (7)

Proton pump (7)

Histone Methyltransferase (7)

c-Met/HGFR (7)

Histamine Receptor (7)

Glucocorticoid Receptor (7)

HSP (7)

Trk receptor (7)

IκB/IKK (7)

c-Myc (6)

Estrogen Receptor/ERR (6)

Tyrosine Kinases (6)

MAO (6)

IL Receptor (6)

PTEN (6)

Lipoxygenase (6)

IGF-1R (6)

P-gp (6)

ALK (6)

Beta Amyloid (6)

GABA Receptor (6)

NADPH (5)

Wnt/beta-catenin (5)

Rho (5)

Cysteine Protease (5)

ROS (5)

ribosome (5)

PDK (5)

Phospholipase (5)

HER (5)

NOS (4)

Carbonic Anhydrase (4)

DHFR (4)

HCV Protease (4)

Integrin (4)

DNA Alkylator/Crosslinker (4)

Progesterone Receptor (4)

MRP (4)

Serine Protease (4)

Serotonin Transporter (4)

Glucokinase (4)

Aryl Hydrocarbon Receptor (4)

IAP (4)

Gamma-secretase (4)

Opioid Receptor (4)

DPP-4 (4)

Hedgehog/Smoothened (4)

GluR (4)

Prostaglandin Receptor (4)

transporter (4)

Reverse Transcriptase (4)

c-Fms (4)

DNA Methyltransferase (4)

FAK (4)

ROS Kinase (4)

Transferase (3)

Dynamin (3)

Amino Acids and Derivatives (3)

Adenosine Receptor (3)

RAAS (3)

ABC (3)

HBV (3)

Pim (3)

Antifolate (3)

SIK (3)

RIP kinase (3)

P2X Receptor (3)

Molecular Glues (3)

Fatty Acid Synthase (3)

DNA (3)

Androgen Receptor (3)

Ligand for E3 Ligase (3)

PLK (3)

SGK (3)

Cannabinoid Receptor (3)

Monoamine Oxidase (3)

NO Synthase (3)

ROR (2)

Ligands for Target Protein for PROTAC (2)

YAP (2)

BACE (2)

DYRK (2)

Cell wall (2)

Glutathione Peroxidase (2)

GTPase (2)

VDA (2)

iGluR (2)

IRE1 (2)

LDL (2)

Drug Metabolite (2)

NMDAR (2)

BTK (2)

Antifection (2)

DNA Alkylation (2)

PGC-1α (2)

CCR (2)

Chk (2)

Norepinephrine (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Interleukin (2)

MAPK (2)

AChE (2)

MNK (2)

Antiviral (2)

Histone Acetyltransferase (2)

CRISPR/Cas9 (2)

GPR (2)

ATTECs (2)

Syk (2)

NOD (2)

BMI-1 (2)

TAM Receptor (2)

Tyrosinase (2)

p97 (2)

lysosomal autophagy (2)

AhR (2)

NOD-like Receptor (NLR) (2)

MLK (2)

S1P Receptor (2)

Adenylyl cyclase (1)

CAT (1)

NPC1L1 (1)

MyD88 (1)

Arginase (1)

LPL Receptor (1)

LTR (1)

Reductase (1)

IFNAR (1)

Arrestin (1)

Na+/Ca2+ Exchanger (1)

RAR/RXR (1)

Histone Demethylase (1)

Lipase (1)

Tie-2 (1)

TOPK (1)

Factor Xa (1)

Melatonin Receptor (1)

Liver X Receptor (1)

Leukotriene Receptor (1)

NAMPT (1)

Glutaminase (1)

FOXO1 (1)

IDO (1)

CSF-1R (1)

Myosin (1)

Annexin A (1)

UGT (1)

PAFR (1)

GRK (1)

DNA gyrase (1)

Glucosidase (1)

Hexokinase (1)

Monoamine Transporter (1)

Guanylate cyclase (1)

Smo (1)

PROTAC Linker (1)

Endothelin Receptor (1)

Somatostatin (1)

ACK (1)

Lipid (1)

ATP Citrate Lyase (1)

OXPHOS (1)

BCRP (1)

Beta-Secretase (1)

Survivin (1)

STING (1)

Aminopeptidase (1)

GPCR19 (1)

Ephrin Receptor (1)

GluCls (1)

PAI-1 (1)

PI4K (1)

Complement System (1)

Gap Junction Protein (1)

Anti-infection (1)

IRAK (1)

Sigma receptor (1)

Thrombin (1)

Imidazoline Receptor (1)

PD-1/PD-L1 (1)

Kinesin (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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