抗寄生虫天然产物库

Antiparasitic Natural Product Library

产品编号： L6620

生活在宿主生物体身上或之内，并从宿主生物体获取食物或以宿主生物体为代价获取食物的生物体，被称为寄生虫。在世界范围内，特别是在热带和亚热带地区，寄生虫所引起的疾病一直是普遍存在的重大公共卫生问题。按照致病的虫种分类，人体寄生虫病主要可以分为原虫病、蠕虫病和节肢动物传播疾病。

天然产物长期以来一直被用于治疗各种寄生虫病，如巴贝西虫病、利什曼病、疟疾、锥虫病等等，并且对非靶标生物毒性低，是抗寄生虫药物先导化合物的重要来源。2015年度诺贝尔生理学颁给从青蒿植物中创造性的研究出抗疟新药的屠呦呦和从高效链霉菌中分离提取得到阿维菌素的大村智和威廉坎贝尔，以表彰他们在寄生虫病治疗研究方面做出的杰出贡献。

TargetMol 抗寄生虫天然产物库，精心整理收录了 253 个具有抗寄生虫活性的天然产物，可用于抗寄生虫新药研发和新靶点验证的多个领域。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

精心挑选253种具有抗寄生虫活性的天然产物，是抗寄生虫药物研发的有力工具；
包含多种抗寄生虫活性天然产物，如抗疟原虫、抗利什曼原虫、抗丝虫病等；
结构多样，包含萜类、生物碱、多酚等类别；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库组成

Parasite (92)

Apoptosis (56)

Antibacterial (51)

Autophagy (40)

Antibiotic (33)

Endogenous Metabolite (30)

Antifungal (22)

NF-κB (16)

Reactive Oxygen Species (12)

Ferroptosis (10)

Antifection (10)

AChR (10)

Topoisomerase (9)

COX (9)

HIV Protease (8)

p38 MAPK (8)

DNA/RNA Synthesis (8)

Influenza Virus (8)

Antioxidant (6)

Caspase (6)

AChE (6)

Potassium Channel (6)

Calcium Channel (5)

PKC (5)

IL Receptor (5)

Anti-infection (5)

Sodium Channel (5)

Microtubule Associated (5)

ATPase (4)

JNK (4)

Mitophagy (4)

Virus Protease (4)

PARP (4)

Mitochondrial Metabolism (4)

ROS (4)

EGFR (4)

Akt (4)

SARS-CoV (4)

ribosome (4)

5-HT Receptor (4)

P450 (4)

TNF (4)

Dehydrogenase (3)

ERK (3)

Glucosidase (3)

BCL (3)

HSV (3)

Nrf2 (3)

Beta Amyloid (3)

AMPK (3)

Phospholipase (3)

GABA Receptor (3)

NOS (2)

Dopamine Receptor (2)

Estrogen/progestogen Receptor (2)

PI3K (2)

Histamine Receptor (2)

Phosphatase (2)

PKA (2)

HBV (2)

Estrogen Receptor/ERR (2)

VEGFR (2)

TRP/TRPV Channel (2)

MAO (2)

Immunology/Inflammation related (2)

UGT (2)

Gamma-secretase (2)

MMP (2)

GluR (2)

Lipoxygenase (2)

TGF-beta/Smad (2)

P-gp (2)

Antiviral (2)

HSP (2)

TLR (2)

STAT (2)

Tyrosinase (2)

FAK (2)

p53 (2)

Chloride channel (1)

Carbonic Anhydrase (1)

Transferase (1)

Hydrogenase (1)

HCV Protease (1)

DYRK (1)

NADPH (1)

Lipase (1)

Factor Xa (1)

ABC (1)

MRP (1)

PPAR (1)

Wnt/beta-catenin (1)

Serotonin Transporter (1)

Serine/threonin kinase (1)

Adrenergic Receptor (1)

iGluR (1)

IAP (1)

PDE (1)

PAFR (1)

MTH1 (1)

Drug Metabolite (1)

NMDAR (1)

DNA gyrase (1)

Monoamine Transporter (1)

Opioid Receptor (1)

Fatty Acid Synthase (1)

Hedgehog/Smoothened (1)

CCR (1)

CXCR (1)

Xanthine Oxidase (1)

Aurora Kinase (1)

cAMP (1)

Epigenetic Reader Domain (1)

CaMK (1)

Androgen Receptor (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

mTOR (1)

Prostaglandin Receptor (1)

Aminopeptidase (1)

Histone Acetyltransferase (1)

transporter (1)

GluCls (1)

RSV (1)

Casein Kinase (1)

IκB/IKK (1)

HDAC (1)

MEK (1)

Platelet aggregation (1)

Syk (1)

NOD (1)

HIF/HIF Prolyl-Hydroxylase (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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