抗肝癌化合物库 | 陶术生物

抗肝癌化合物库

Anti-Liver Cancer Compound Library

产品编号： L2193

在全球范围内，肝癌占癌症死亡率第三位。肝癌的主要病因包括乙肝、丙肝、酒精性脂肪性肝炎和非酒精性脂肪性肝炎（NASH）。许多细胞信号通路与肝癌的发生有关，如 PI3K/Akt/mTOR 信号通路，表皮生长因子受体(EGFR)、血管内皮生长因子受体(VEGFR)等

TargetMol 抗肝癌化合物库收集了 1816 种与肝癌相关的化合物，包括已经报道具有肝癌治疗作用的化合物，以及靶向肝癌相关靶点潜在治疗肝癌的化合物，是抗肝癌药物研发的良好工具。

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产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

1816种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
通路靶点包含PI3K/Akt/mTOR，EGFR, FGFR，Met等；
部分化合物已上市或进入临床期；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Apoptosis (355)

Autophagy (281)

NF-κB (206)

Reactive Oxygen Species (163)

PI3K (156)

EGFR (144)

VEGFR (141)

Endogenous Metabolite (90)

JAK (88)

Akt (85)

mTOR (85)

ERK (82)

p38 MAPK (81)

STAT (79)

FGFR (73)

Antibacterial (71)

PDGFR (67)

Raf (66)

c-Met/HGFR (64)

AMPK (60)

CDK (59)

Ras (59)

GSK-3 (52)

TGF-beta/Smad (52)

FLT (51)

c-Kit (49)

JNK (45)

COX (44)

Src (44)

MEK (42)

MAPK (41)

IκB/IKK (38)

DNA/RNA Synthesis (37)

HER (37)

DNA-PK (36)

TNF (34)

Ferroptosis (30)

Parasite (30)

S6 Kinase (30)

Antibiotic (28)

Tyrosine Kinases (28)

HIV Protease (27)

IL Receptor (25)

Mitophagy (24)

ALK (23)

c-RET (23)

ATM/ATR (22)

RIP kinase (22)

Antifungal (21)

Bcr-Abl (21)

Caspase (21)

Potassium Channel (21)

NOD (20)

PKC (20)

Influenza Virus (19)

PDK (19)

Antioxidant (17)

Aurora Kinase (17)

P450 (17)

ROS (17)

IRAK (16)

Calcium Channel (15)

Pim (15)

Topoisomerase (15)

Casein Kinase (14)

IGF-1R (14)

TAM Receptor (14)

NO Synthase (13)

NOD-like Receptor (NLR) (13)

PI4K (13)

PKA (13)

PPAR (13)

Trk receptor (13)

c-Fms (12)

Dehydrogenase (12)

Interleukin (12)

Microtubule Associated (12)

Mitochondrial Metabolism (12)

MMP (12)

Rho (12)

Lipoxygenase (11)

Nucleoside Antimetabolite/Analog (11)

PD-1/PD-L1 (11)

5-HT Receptor (10)

HCV Protease (10)

HDAC (10)

Sodium Channel (10)

Virus Protease (10)

AChR (9)

Chk (9)

FAK (9)

HBV (9)

HIF/HIF Prolyl-Hydroxylase (9)

Nrf2 (9)

ROCK (9)

Adrenergic Receptor (8)

BCL (8)

Estrogen/progestogen Receptor (8)

HSP (8)

Proteasome (8)

PTEN (8)

Syk (8)

Tyrosinase (8)

Wnt/beta-catenin (8)

Beta Amyloid (7)

HSV (7)

NOS (7)

p53 (7)

PDE (7)

Reverse Transcriptase (7)

SARS-CoV (7)

TLR (7)

BTK (6)

DNA Alkylator/Crosslinker (6)

E1/E2/E3 Enzyme (6)

GABA Receptor (6)

PLK (6)

AChE (5)

Adenosine Receptor (5)

Antiviral (5)

ASK (5)

CSF-1R (5)

Drug Metabolite (5)

Ephrin Receptor (5)

Estrogen Receptor/ERR (5)

HIF (5)

Histamine Receptor (5)

Histone Methyltransferase (5)

MELK (5)

MLK (5)

MNK (5)

PARP (5)

Phosphatase (5)

SGK (5)

SIK (5)

TOPK (5)

Transferase (5)

Aryl Hydrocarbon Receptor (4)

ATPase (4)

CaMK (4)

DNA Alkylation (4)

Integrin (4)

NADPH (4)

P-gp (4)

Prostaglandin Receptor (4)

RAAS (4)

Serine Protease (4)

Tie-2 (4)

Antifection (3)

Anti-infection (3)

BACE (3)

Cannabinoid Receptor (3)

Carbonic Anhydrase (3)

CCR (3)

Chloride channel (3)

cholecystokinin (3)

Discoidin Domain Receptor (DDR) (3)

Epigenetic Reader Domain (3)

Free radical scavengers (3)

Glucocorticoid Receptor (3)

Glucosidase (3)

Glutathione Peroxidase (3)

Histone Acetyltransferase (3)

IFNAR (3)

KLF (3)

LRRK2 (3)

Opioid Receptor (3)

PGE Synthase (3)

Proton pump (3)

ROS Kinase (3)

Sirtuin (3)

Antifolate (2)

Aromatase (2)

Beta-Secretase (2)

c-Myc (2)

DHFR (2)

DPP-4 (2)

Fatty Acid Synthase (2)

Glutathione reductase (2)

GST (2)

GTPase (2)

Hck (2)

Hedgehog/Smoothened (2)

HMG-CoA Reductase (2)

IRE1 (2)

Kinesin (2)

Leukotriene Receptor (2)

MAO (2)

NADPH-oxidase (2)

PERK (2)

Phospholipase (2)

RANKL/RANK (2)

Retinoid Receptor (2)

ROR (2)

RSV (2)

S1P Receptor (2)

Somatostatin (2)

transporter (2)

TRP/TRPV Channel (2)

ABC (1)

ACK (1)

Adenosine deaminase (1)

AhR (1)

Aminopeptidase (1)

Androgen Receptor (1)

ATP Citrate Lyase (1)

BCRP (1)

BMI-1 (1)

cAMP (1)

CFTR (1)

cGAS (1)

Complement System (1)

CRISPR/Cas9 (1)

Cysteine Protease (1)

DAPK (1)

DNA (1)

DNA Methyltransferase (1)

Dopamine Receptor (1)

DUB (1)

DYRK (1)

FAAH (1)

FXR (1)

Gamma-secretase (1)

Gap Junction Protein (1)

Glucokinase (1)

GluR (1)

GPR (1)

GPX (1)

Haspin Kinase (1)

hCE (1)

Hippo pathway (1)

Hydroxylase (1)

IAP (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

KSP (1)

LDL (1)

Liver X Receptor (1)

LTR (1)

Mdm2 (1)

Melanin-concentrating Hormone Receptor (MCHR) (1)

Monoamine Oxidase (1)

MRP (1)

Myosin (1)

Na+/Ca2+ Exchanger (1)

NEDD8 (1)

NPC1L1 (1)

OCT (1)

OXPHOS (1)

PAI-1 (1)

PAK (1)

PKM (1)

Platelet aggregation (1)

Progesterone Receptor (1)

PYK2 (1)

Pyroptosis (1)

RAR/RXR (1)

Reductase (1)

Serine/threonin kinase (1)

Serotonin Transporter (1)

SGLT (1)

Sigma receptor (1)

STING (1)

Telomerase (1)

Thrombin (1)

Thrombopoietin Receptor (1)

UGT (1)

Wee1 (1)

YAP (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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