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PPP1R1A Protein, Human, Recombinant (His)

PPP1R1A Protein, Human, Recombinant (His)

产品编号 TMPJ-00528
别名: PPP1R1A, I-1, IPP-1, Protein Phosphatase Inhibitor 1, Protein Phosphatase 1 Regulatory Subunit 1A, IPP1

Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.

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PPP1R1A Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 820 5日内发货
50 μg ¥ 2,480 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: PPP1R1A Protein, Human, Recombinant (His) (TMPJ-00528)
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产品描述 Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
种属 Human
表达系统 E. coli
标签 C-6His
蛋白编号 AAH22470.1
别名 PPP1R1A, I-1, IPP-1, Protein Phosphatase Inhibitor 1, Protein Phosphatase 1 Regulatory Subunit 1A, IPP1
氨基酸序列 Met1-Val171
蛋白构建 Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A is produced by our E.coli expression system and the target gene encoding Met1-Val171 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 18 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.5.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.

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Keywords

PPP1R1A Protein, Human, Recombinant (His) PPP1R1A IPP 1 I-1 IPP-1 Protein Phosphatase Inhibitor 1 Protein Phosphatase 1 Regulatory Subunit 1A IPP1 I 1 I1 recombinant recombinant-proteins proteins protein

 

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