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Phosphatase
T0745 Disodium monofluorophosphate Sodium Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase, which also irreversibly inhibits phosphorylase phosphatase.
T0945 Cyclosporin A Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhibitor, and P-Glycopr
T1927 CCT007093 CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).
T2189 Sodium orthovanadate Oxyvanadium ions in various states of oxidation. They act primarily as ion transport inhibitors due to their inhibition of Na(+)-, K(+)-, and Ca(+)-ATPase transport systems. They a
T2481 Ascomycin Ascomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
T3544 SHP099 hydrochloride SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
T4340 SPI 112 SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinet
T6459 Cyclosporine Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
T6521 GSK2830371 GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
T6911 NSC87877 NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and
T4256 PTP1B-IN-2 PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
T4308 F1063-0967 F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.
T4491 LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base)) LMPTP INHIBITOR 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A.
T7084 PTP Inhibitor I PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phospha
T4671 CDC25 Phosphatase Inhibitor I BN82002 is a synthetic inhibitor of CDC25 phophatases
T5708 LUPENONE Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhibitors with IC50 val
T5878 β-Glycerol phosphate disodium salt pentahydrate β-Glycerol phosphate disodium salt pentahydrate is a protein phosphatase inhibitor.
T7381 TCS 401 TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 μM)
T7356 PTP1B-IN-1 PTP1B-IN-1 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)
T7541 PTP Inhibitor II PTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing pho
T7704 KY-226 KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)
T7078 NSC 95397 NSC 95397 is a  potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).
TQ0032 Rosiptor Rosiptor (AQX-1125) is an orally-active and specific phosphatase SHIP1 activator with anti-inflammatory effects.
T7820 Raphin1 Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B).
T7028 LICOCHALCONEC Licochalcone C has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, an
TN1053 Aloe-emodin-8-O-beta-D-glucopyranoside Aloe-emodin-8-O-beta-D-glucopyranoside shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
T12577 PTP1B-IN-3 PTP1B-IN-3 is a potent and selective inhibitor of PTP1B (PTP1B and TCPTP with IC50s of 120 nM and 120 nM , respectively).
T12578 PTP1B-IN-8 PTP1B-IN-8 is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B).
T14037 3α-Aminocholestane 3α-Aminocholestane , a selective SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) , inhibitor with an IC50 of ~2.5 μM.
T13176 TNO155 TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplast
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