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纤维生长因子受体

纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs) 是与纤维生长因子 (Fibroblast Growth Factor ,FGF) 蛋白家族成员结合的受体。FGFR 由一个由三个免疫球蛋白样结构域组成的细胞外配体结构域、一个跨膜螺旋结构域和一个具有酪氨酸激酶活性的细胞内结构域组成。FGF/FGFR信号通路与多种癌症有关。目前有作用于所有 FGFR1-4 和其他蛋白质的非选择性 FGFR 抑制剂,以及作用于部分/全部 FGFR1-4 的一些选择性 FGFR 抑制剂,例如AZD4547、BGJ398、JNJ42756493和PD173074。

目录号 产品名/同用名 种属 表达系统
TMPY-01360 FGFRL1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-01781 FGFR1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-01782 FGFR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-02635 FGFR4 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
TMPY-02853 FGFR3 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
TMPY-02862 FGFR4 Protein, Rat, Recombinant (His) Rat HEK293 Cells
TMPY-03322 FGFR4 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293 Cells
TMPY-03350 FGFR1 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293 Cells
TMPY-03389 FGFR2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-03455 FGFR1OP Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
TMPY-03683 FGFR4 Protein, Rhesus, Recombinant (His) Rhesus HEK293 Cells
TMPY-03926 FGFR1 Protein, Rhesus, Recombinant (His) Rhesus HEK293 Cells
TMPY-04200 FGFR3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His) Human HEK293 Cells
TMPY-04371 FGFR1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
TMPY-04390 FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) Human Baculovirus Insect Cells
TMPY-05761 FGFR1 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
TMPY-05777 FGFR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-06033 FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) Human HEK293 Cells
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) Human HEK293 Cells
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