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刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。

目录号 产品名/同用名 种属 表达系统
TMPK-00260 CD155/PVR Protein, Human, Recombinant (His & Avi) Human HEK293
TMPK-00280 B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TMPK-00314 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) Human HEK293
TMPK-00315 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TMPK-00463 OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293
TMPK-00464 OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
TMPK-00653 B7-2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TMPK-00666 CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TMPK-00860 CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc) Mouse HEK293
TMPK-00880 B7-2 Protein, Human, Recombinant (His & Avi) Human HEK293
TMPK-00881 B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TMPK-00882 B7-2 Protein, Human, Recombinant (hFc) Human HEK293
TMPK-01016 B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled Human HEK293
TMPK-01017 B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) Human HEK293
TMPK-01018 B7-H3 Protein, Human, Recombinant (aa 29-245, His) Human HEK293
TMPK-01086 GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His) Mouse HEK293
TMPK-01176 CD28 Protein, Canine, Recombinant (His) Canine HEK293
TMPK-01177 CD28 Protein, Canine, Recombinant (mFc) Canine HEK293
TMPK-01260 GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His) Cynomolgus HEK293
TMPK-01398 CD40 Ligand Trimer Protein, Human, Recombinant (hFc) Human HEK293
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