×
{{login.error}}
{{login.verifyresult}}
×
6~16个字符、区分大小写、必须包含字母和数字
6~16个字符、区分大小写、必须包含字母和数字
密码已经重置成功,快去使用新密码吧!
登录账号
密码已经重置成功,快去使用新密码吧! 登录账号
×

注册成功

确认
high_solubility_fragment_library
/library/high_solubility_fragment_library
高溶解性片段库
High Solubility Fragment Library
产品编号: L7800

FBDD 方法的前提是建立高品质的片段库,片段分子往往需要满足“三规则”,分子量小于300,氢键供体和受体不超过3,可旋转键数目不超过3,cLogP 小于3。高溶解性片段库按照“三规则”建立,绝大部分片段分子量小于300,氢键供体与受体数量均不高于3,且每个片段均测试过溶解度:DMSO (200 mM)与 PBS(1 mM )。

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
产品规格
  • 数量:2728种片段分子合集,数量适中,是FBDD方法新药筛选的有力工具。
  • 药化性质:化合物库依据Fragment的RO3原则构建进行,具有优良的药化性质,便于后续结构优化。
  • 多样性:药效团丰富,极大的覆盖了可能的空间结构。每一个分子在设计之初的时候均考虑了结构的多样性和新颖性。
  • 溶解度:保证在DMSO和PBS buffer中的溶解度:DMSO (200 mM) ,PBS (1 mM)。
  • 适用方法多样:适合SPR,核磁,X射线单晶衍射等多种检测手段进行新药开发。
化合物库定制
我们的化合物库可以灵活定制!了解更多
化合物库咨询
化合物库组成
Endogenous Metabolite (26)
Antibacterial (11)
Apoptosis (8)
Autophagy (7)
Sodium Channel (5)
AChR (4)
HCV Protease (3)
Antifungal (3)
Antioxidant (3)
Histamine Receptor (3)
COX (3)
Influenza Virus (3)
Anti-infection (3)
Antibiotic (3)
Ferroptosis (2)
Mitophagy (2)
PPAR (2)
Parasite (2)
Adrenergic Receptor (2)
MAO (2)
Drug Metabolite (2)
IL Receptor (2)
DNA/RNA Synthesis (2)
AChE (2)
Aromatase (2)
NF-κB (2)
5-HT Receptor (2)
Monoamine Oxidase (2)
HIV Protease (1)
CAT (1)
Carbonic Anhydrase (1)
Dehydrogenase (1)
JNK (1)
Virus Protease (1)
MRP (1)
Tyrosine Kinases (1)
Nucleoside Antimetabolite/Analog (1)
TRP/TRPV Channel (1)
ERK (1)
iGluR (1)
Adiponectin receptor (1)
PDE (1)
CDK (1)
Reactive Oxygen Species (1)
DPP-4 (1)
JAK (1)
FAAH (1)
HSV (1)
MMP (1)
Aurora Kinase (1)
Interleukin (1)
ATP Citrate Lyase (1)
Akt (1)
Acyltransferase (1)
Antiviral (1)
Trk receptor (1)
Free radical scavengers (1)
Reverse Transcriptase (1)
Retinoid Receptor (1)
STAT (1)
AMPK (1)
Phospholipase (1)
P450 (1)
TNF (1)
Potassium Channel (1)
Platelet aggregation (1)
化合物库信息示例
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
联系我们
400-820-0310
service@tsbiochem.com

上海市静安区江场三路238号8楼