抗氧化化合物库 | 陶术生物

抗氧化化合物库

Antioxidant Compound Library

产品编号： L2910

氧化应激（Oxidative Stress，OS）是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧（ROS）大量积累，氧化程度超出抗氧化物的清除能力，从而引起氧化损伤，氧化应激损伤是许多疾病发生的基础，不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激，降低氧化损伤的一类化合物。

TargetMol 抗氧化化合物库是1314 种对氧化应激具有抑制作用的小分子特有集合，是研究氧化应激的有用工具，可以用于高通量筛选和高内涵筛选。

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产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

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产品描述

1314种抗氧化生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选；
靶点含mTOR, Keap1‐Nrf2, ROS, NF-κB等；
结构多样，药效显著，可渗透细胞；
详细的说明书、化合物结构、靶点信息、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Apoptosis (240)

NF-κB (229)

PI3K (190)

Autophagy (178)

Reactive Oxygen Species (138)

Antioxidant (118)

Endogenous Metabolite (117)

mTOR (103)

Akt (93)

Antibacterial (87)

AMPK (80)

COX (56)

GSK-3 (49)

ROS (49)

ERK (42)

TNF (37)

DNA-PK (35)

Antifungal (35)

p38 MAPK (30)

Influenza Virus (29)

S6 Kinase (29)

CDK (28)

Ferroptosis (27)

Nrf2 (27)

HIV Protease (25)

Parasite (25)

JNK (24)

IL Receptor (24)

Caspase (21)

ATM/ATR (20)

STAT (19)

Mitophagy (18)

P450 (18)

Antibiotic (18)

PPAR (17)

NO Synthase (17)

MMP (16)

Calcium Channel (15)

PKC (15)

Lipoxygenase (15)

PDK (15)

Tyrosinase (15)

DNA/RNA Synthesis (14)

Beta Amyloid (14)

Src (12)

Virus Protease (12)

PKA (12)

VEGFR (12)

Mitochondrial Metabolism (12)

Glutathione Peroxidase (11)

BCL (11)

HSV (11)

NOS (10)

Dehydrogenase (10)

Wnt/beta-catenin (10)

AChE (10)

IκB/IKK (10)

PI4K (10)

MEK (10)

ROS Kinase (10)

MAPK (9)

AChR (9)

Anti-infection (9)

HIF/HIF Prolyl-Hydroxylase (9)

Xanthine Oxidase (8)

Interleukin (8)

Casein Kinase (8)

HDAC (8)

Phosphatase (7)

Topoisomerase (7)

PDE (7)

Chk (7)

P-gp (7)

ALK (7)

GABA Receptor (7)

Potassium Channel (7)

FLT (7)

Proteasome (6)

Estrogen/progestogen Receptor (6)

PARP (6)

ROCK (6)

Adrenergic Receptor (6)

PTEN (6)

EGFR (6)

TLR (6)

Free radical scavengers (6)

5-HT Receptor (6)

HIF (6)

p53 (6)

Carbonic Anhydrase (5)

HCV Protease (5)

c-Met/HGFR (5)

HBV (5)

TRP/TRPV Channel (5)

SIK (5)

E1/E2/E3 Enzyme (5)

Bcr-Abl (5)

JAK (5)

Aurora Kinase (5)

Epigenetic Reader Domain (5)

IGF-1R (5)

Antiviral (5)

Prostaglandin Receptor (5)

transporter (5)

ATPase (4)

Chloride channel (4)

Adenosine Receptor (4)

Reductase (4)

BACE (4)

RAAS (4)

MAO (4)

Immunology/Inflammation related (4)

Glucosidase (4)

PDGFR (4)

GluR (4)

CaMK (4)

TGF-beta/Smad (4)

HSP (4)

SARS-CoV (4)

MELK (4)

FGFR (4)

Sodium Channel (4)

Microtubule Associated (4)

FAK (4)

Integrin (3)

NADPH (3)

Histamine Receptor (3)

IAP (3)

LDL (3)

Raf (3)

NMDAR (3)

Opioid Receptor (3)

PGE Synthase (3)

Trk receptor (3)

Sirtuin (3)

GPX (3)

PLK (3)

NOD (3)

NOD-like Receptor (NLR) (3)

Transferase (2)

NPC1L1 (2)

ROR (2)

Dopamine Receptor (2)

LTR (2)

Melatonin Receptor (2)

Estrogen Receptor/ERR (2)

Tyrosine Kinases (2)

Rho (2)

Serine Protease (2)

Serine/threonin kinase (2)

Cysteine Protease (2)

Leukotriene Receptor (2)

iGluR (2)

Gamma-secretase (2)

Antifection (2)

Fatty Acid Synthase (2)

Hedgehog/Smoothened (2)

Androgen Receptor (2)

Telomerase (2)

SGLT (2)

ATP Citrate Lyase (2)

Beta-Secretase (2)

Histone Acetyltransferase (2)

RSV (2)

GST (2)

Reverse Transcriptase (2)

Retinoid Receptor (2)

Phospholipase (2)

Oxytocin Receptor (2)

c-RET (2)

SGK (2)

Cannabinoid Receptor (2)

Platelet aggregation (2)

Syk (2)

Ras (2)

HMG-CoA Reductase (2)

cholecystokinin (2)

Monoamine Oxidase (2)

S1P Receptor (2)

advanced glycation end products (1)

Mdm2 (1)

stilbene oxidase (1)

Dynamin (1)

Amino Acids and Derivatives (1)

MyD88 (1)

YAP (1)

RAR/RXR (1)

DYRK (1)

PERK (1)

Tie-2 (1)

OCT (1)

c-Myc (1)

MRP (1)

Hck (1)

Liver X Receptor (1)

Glucokinase (1)

RANKL/RANK (1)

Amylase (1)

Aryl Hydrocarbon Receptor (1)

Glucocorticoid Receptor (1)

Myosin (1)

MTH1 (1)

Drug Metabolite (1)

MT Receptor (1)

Phosphorylase (1)

Smo (1)

DPP-4 (1)

PAK (1)

Stearoyl-CoA Desaturase (SCD) (1)

CCR (1)

Bradykinin Receptor (1)

Somatostatin (1)

Epoxide Hydrolase (1)

cAMP (1)

DUB (1)

BCRP (1)

OXPHOS (1)

Glutathione reductase (1)

OAT (1)

STING (1)

Aminopeptidase (1)

Pyroptosis (1)

Acetyl-CoA Carboxylase (1)

c-Fms (1)

Aromatase (1)

CRISPR/Cas9 (1)

Adenosine deaminase (1)

Complement System (1)

Discoidin Domain Receptor (DDR) (1)

c-Kit (1)

NADPH-oxidase (1)

DNA Methyltransferase (1)

IRAK (1)

AhR (1)

CFTR (1)

HER (1)

PKM (1)

Kinesin (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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