抗感染化合物库 | 陶术生物

抗感染化合物库

Anti-Infection Compound Library

产品编号： L1800

当外来生物进入人体并造成伤害时就会发生感染，这些引起感染的外来生物称为病原体，例如细菌、病毒、真菌和寄生虫等。有些感染是轻微的几乎不可察觉，但有些感染严重甚至危及生命，且对治疗有抵抗力。

针对上述情况，TargetMol 精选了2938 种具有抗菌、抗病毒以及抗寄生虫等抗感染活性的化合物的组成抗感染化合物库，以用于抗感染研究中的药物高通量筛选、确认药物靶点以及其他医药研发和科研领域。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

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产品描述

2938种具有抗感染活性的化合物的特有集合，包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性；
含有磺胺类，氨基糖苷类，四环素类和大环内酯类等化合物，是筛选新型抗感染药的有效工具；可用于高通量筛选和高内涵筛选；
通过前期临床研究和临床实验，生物活性和安全性已经得到验证；其中一些抗感染化合物已得到FDA批准上市；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Antibacterial (754)

Antibiotic (502)

Parasite (224)

Antifungal (220)

Autophagy (190)

Apoptosis (183)

Endogenous Metabolite (177)

HIV Protease (170)

Influenza Virus (123)

DNA/RNA Synthesis (92)

SARS-CoV (66)

Virus Protease (64)

HCV Protease (61)

HSV (54)

Anti-infection (51)

HBV (50)

NF-κB (45)

Topoisomerase (44)

Nucleoside Antimetabolite/Analog (42)

Reactive Oxygen Species (40)

Reverse Transcriptase (40)

P450 (37)

COX (35)

Antiviral (35)

ribosome (31)

Dehydrogenase (27)

Antifection (24)

Mitophagy (21)

AChE (20)

Ferroptosis (19)

Antioxidant (19)

AChR (19)

Histamine Receptor (18)

PKC (18)

GABA Receptor (18)

Microtubule Associated (18)

ATPase (17)

Proton pump (17)

STAT (17)

Potassium Channel (17)

Dopamine Receptor (16)

Adenosine Receptor (16)

Phosphatase (16)

Sodium Channel (16)

PI3K (15)

MMP (15)

TLR (15)

p38 MAPK (14)

Calcium Channel (14)

IL Receptor (14)

HDAC (14)

Caspase (13)

Adrenergic Receptor (13)

ROS (13)

CCR (13)

Akt (13)

AMPK (12)

TNF (12)

Tyrosinase (12)

Estrogen/progestogen Receptor (11)

PPAR (11)

PARP (11)

DNA gyrase (11)

Phospholipase (11)

5-HT Receptor (11)

BCL (10)

ERK (9)

Mitochondrial Metabolism (9)

mTOR (9)

HIF/HIF Prolyl-Hydroxylase (9)

PKA (8)

MAO (8)

PDE (8)

CXCR (8)

Epigenetic Reader Domain (8)

P-gp (8)

Nrf2 (8)

RSV (8)

DNA Methyltransferase (8)

NO Synthase (8)

CAT (7)

DHFR (7)

Serine/threonin kinase (7)

TRP/TRPV Channel (7)

Glucocorticoid Receptor (7)

CDK (7)

Glucosidase (7)

JAK (7)

Lipoxygenase (7)

EGFR (7)

HSP (7)

IRAK (7)

Estrogen Receptor/ERR (6)

Cysteine Protease (6)

Drug Metabolite (6)

NMDAR (6)

CaMK (6)

Retinoid Receptor (6)

Proteasome (5)

Chloride channel (5)

Carbonic Anhydrase (5)

Transferase (5)

DprE1 (5)

IFNAR (5)

NADPH (5)

Serine Protease (5)

Gamma-secretase (5)

DNA (5)

Lipid (5)

S6 Kinase (5)

Monoamine Oxidase (5)

NOS (4)

Histone Methyltransferase (4)

Src (4)

Reductase (4)

Cell wall (4)

JNK (4)

Tyrosine Kinases (4)

Antifolate (4)

VEGFR (4)

Opioid Receptor (4)

Fatty Acid Synthase (4)

Interleukin (4)

TGF-beta/Smad (4)

STING (4)

Aminopeptidase (4)

Sirtuin (4)

transporter (4)

Beta Amyloid (4)

PI4K (4)

MEK (4)

Thrombin (4)

p53 (4)

Thyroid hormone receptor(THR) (3)

DNA-PK (3)

CRM1 (3)

P2Y Receptor (3)

GSK-3 (3)

ABC (3)

MRP (3)

FXR (3)

iGluR (3)

Bcr-Abl (3)

P2X Receptor (3)

PDGFR (3)

Hedgehog/Smoothened (3)

Chk (3)

Xanthine Oxidase (3)

cAMP (3)

Androgen Receptor (3)

Acyltransferase (3)

IκB/IKK (3)

ATM/ATR (3)

GPR (3)

HIF (3)

Adenosine deaminase (3)

NADPH-oxidase (3)

Ras (3)

FAK (3)

Integrin (2)

Arginase (2)

BACE (2)

Histone Demethylase (2)

Glutathione Peroxidase (2)

Progesterone Receptor (2)

Wnt/beta-catenin (2)

IAP (2)

Annexin A (2)

UGT (2)

PAFR (2)

Raf (2)

Monoamine Transporter (2)

Guanylate cyclase (2)

Integrase (2)

DNA Alkylation (2)

Stearoyl-CoA Desaturase (SCD) (2)

Aurora Kinase (2)

GluR (2)

Norepinephrine (2)

DUB (2)

Telomerase (2)

MAPK (2)

Prostaglandin Receptor (2)

Free radical scavengers (2)

GPCR19 (2)

Histone Acetyltransferase (2)

GluCls (2)

Casein Kinase (2)

Aromatase (2)

CRISPR/Cas9 (2)

PLK (2)

Cannabinoid Receptor (2)

Complement System (2)

Platelet aggregation (2)

Syk (2)

NOD (2)

HMG-CoA Reductase (2)

NOD-like Receptor (NLR) (2)

AhR (2)

PKM (2)

S1P Receptor (2)

Mdm2 (1)

Hydrogenase (1)

CYP19A1 (1)

ROR (1)

Dynamin (1)

Amino Acids and Derivatives (1)

YAP (1)

c-Met/HGFR (1)

DNA Alkylator/Crosslinker (1)

LTR (1)

Arrestin (1)

RAAS (1)

PERK (1)

Lipase (1)

gp120/CD4 (1)

TOPK (1)

Factor Xa (1)

VDA (1)

GNRH Receptor (1)

Rho (1)

Hck (1)

Serotonin Transporter (1)

cell cycle arrest (1)

Liver X Receptor (1)

Leukotriene Receptor (1)

LIM Kinase (1)

Glucokinase (1)

ROCK (1)

Amylase (1)

Aryl Hydrocarbon Receptor (1)

Immunology/Inflammation related (1)

IRE1 (1)

E1/E2/E3 Enzyme (1)

RIP kinase (1)

Adiponectin receptor (1)

Hexokinase (1)

Bombesin Receptor (1)

FAAH (1)

Endothelin Receptor (1)

PTEN (1)

Somatostatin (1)

Epoxide Hydrolase (1)

IGF-1R (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

ATP Citrate Lyase (1)

BCRP (1)

PGE Synthase (1)

Glutathione reductase (1)

ASK (1)

Pyroptosis (1)

GST (1)

Acetyl-CoA Carboxylase (1)

Carboxypeptidase (1)

PDK (1)

Hydroxylase (1)

CGRP Receptor (1)

SGK (1)

ATTECs (1)

Neurokinin receptor (1)

Gap Junction Protein (1)

FLT (1)

c-Kit (1)

BMI-1 (1)

TAM Receptor (1)

PD-1/PD-L1 (1)

HER (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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