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anti-ovarian_cancer_compound_library
/library/anti-ovarian_cancer_compound_library
抗卵巢癌化合物库
Anti-Ovarian Cancer Compound Library
产品编号: L2196

卵巢癌是一种恶性肿瘤,起源于女性卵巢组织,其中,90%~95%的卵巢癌是原发性癌,即起源于卵巢本身;另外5%~10%的癌症是从其他部位扩散到卵巢的转移癌。卵巢癌的早期阶段通常没有明显症状,即使有症状也不具备特异性,因此早期诊断相对困难。大约60%~70%的患者在就诊时已经进入晚期,而晚期患者的治疗效果较差。虽然卵巢癌的发病率低于宫颈癌和子宫内膜癌,但卵巢癌的死亡率超过了宫颈癌和子宫内膜癌的总和,并且卵巢癌的死亡率呈逐年上升的趋势,严重威胁着女性的健康。如何有效的提高卵巢癌患者的生存期已成为妇科肿瘤亟待攻克的难题。 近年来,分子靶向药物研发取得了突飞猛进的进展。研究发现,针对卵巢癌相关治疗靶点的药物在提升患者生存期方面发挥了显著作用。靶向药物的开发为卵巢癌患者带来了希望,为他们提供了更有效的治疗策略。 TargetMol 抗卵巢癌化合物库收集了1867 种与卵巢癌相关的化合物,包括已经报道具有治疗卵巢癌作用的化合物,以及潜在治疗卵巢癌的化合物,是抗卵巢癌药物研发的良好工具。

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
产品规格
  • 1867种与卵巢癌相关的化合物,可以用于抗卵巢癌药物研发和药理研究;
  • 通路靶点包含PARP、VEGF、PD-1、HER2等;
  • 部分化合物已上市或进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。
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化合物库组成
Apoptosis (319)
Autophagy (252)
NF-κB (226)
PI3K (179)
EGFR (163)
Reactive Oxygen Species (155)
VEGFR (146)
mTOR (96)
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ERK (92)
p38 MAPK (91)
Endogenous Metabolite (88)
Wnt/beta-catenin (86)
AMPK (81)
Estrogen Receptor/ERR (79)
PARP (73)
Raf (70)
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GSK-3 (59)
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CDK (57)
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TGF-beta/Smad (50)
JNK (48)
MAPK (45)
MEK (45)
FGFR (42)
Src (41)
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IκB/IKK (40)
c-Kit (40)
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DNA-PK (37)
TNF (32)
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化合物库信息示例
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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