Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 880 | 5日内发货 | ||
50 μg | ¥ 2,660 | 5日内发货 | ||
500 μg | ¥ 12,400 | 5日内发货 | ||
1 mg | ¥ 18,700 | 5日内发货 |
产品描述 | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
种属 | Human |
表达系统 | Human Cells |
标签 | C-6His |
蛋白编号 | P05556 |
别名 | Integrin Beta-1, VLA-4 Subunit β, Fibronectin Receptor Subunit Beta, Fibronectin Receptor Subunit β, CD29, ITGB1, Integrin β-1, VLA-4 Subunit Beta, FNRB, MDF2, MSK12 |
氨基酸序列 | Gln21-Asp728 |
蛋白构建 | Recombinant Human Integrin β-1/ITGB1 is produced by our Mammalian expression system and the target gene encoding Gln21-Asp728 is expressed with a 6His tag at the C-terminus. |
蛋白纯度 | Greater than 90% as determined by reducing SDS-PAGE. Greater than 90% as determined by SEC-HPLC. |
分子量 | 100-130 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
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ITGB1 Protein, Human, Recombinant (aa 21-728, His) Integrin Beta-1 VLA-4 Subunit β ITGB 1 Integrin b-1 MDF 2 Fibronectin Receptor Subunit Beta Fibronectin Receptor Subunit β MSK-12 CD-29 CD29 ITGB1 Integrin β-1 VLA-4 Subunit Beta MDF-2 CD 29 FNRB MDF2 ITGB-1 MSK12 MSK 12 recombinant recombinant-proteins proteins protein