ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)

Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

规格	价格/CNY		数量
10 μg	￥ 510	5日内发货
50 μg	￥ 1,570	5日内发货
500 μg	￥ 12,800	5日内发货
1 mg	￥ 19,200	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 510

5日内发货

50 μg

￥ 1,570

5日内发货

500 μg

￥ 12,800

5日内发货

1 mg

￥ 19,200

5日内发货

产品描述

种属	Rhesus Macaque
表达系统	Human Cells
标签	C-Fc
蛋白编号	Q5NKV6
别名	Intercellular adhesion molecule 1, ICAM1, CD54, ICAM-1
氨基酸序列	Gln28-Glu480
蛋白构建	Recombinant Intercellular adhesion molecule 1 is produced by our Mammalian expression system and the target gene encoding Gln28-Glu480 is expressed with a human IgG1 Fc tag at the C-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	100-130 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

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ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)

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