CD98 Protein, Human, Recombinant (mFc)

CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.

规格	价格/CNY		数量
10 μg	￥ 410	5日内发货
50 μg	￥ 1,270	5日内发货
500 μg	￥ 10,000	5日内发货
1 mg	￥ 15,100	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 410

5日内发货

50 μg

￥ 1,270

5日内发货

500 μg

￥ 10,000

5日内发货

1 mg

￥ 15,100

5日内发货

生物活性

1. Loaded Anti-Human CD98 mAb-Fc on AHC Biosensor, can bind Human CD98-mFc with an affinity constant of <10^-3 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Human CD98-mFc at 2μg/ml (100 μl/well) can bind Anti-Human CD98 mAb . The ED50 of Anti-Human CD98 mAb is 1.34 ng/ml. (Regularly tested)

产品描述

种属	Human
表达系统	Human Cells
标签	N-mFc
蛋白编号	P08195
别名	Lymphocyte activation antigen 4F2 large subunit, 4F2 cell-surface antigen heavy chain, CD98, MDU1, SLC3A2, 4F2hc, Solute carrier family 3 member 2
氨基酸序列	Arg206-Ala630
蛋白构建	Recombinant Human 4F2 Cell-surface Antigen Heavy Chain is produced by our Mammalian expression system and the target gene encoding Arg206-Ala630 is expressed with a mFc tag at the N-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	70-100 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4.
存储	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输方式	The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
研究背景	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.

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CD98 Protein, Human, Recombinant (mFc)

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