CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated

Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.

规格	价格/CNY		货期	数量
20 μg	￥ 2,170	20日内发货
100 μg	￥ 3,360	20日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 2,170

20日内发货

100 μg

￥ 3,360

20日内发货

生物活性

Measured by its binding ability in a functional ELISA. Immobilized Anti-CD44 Mouse Monoclonal Antibody at 2 μg/mL can bind Biotinylated human CD44, the EC 50 is 2.865-5.099 ng/mL.

产品描述

种属	Human
表达系统	HEK293
标签	C-terminal mFc-Avi-tagged
蛋白编号	P16070
别名	HUTCH-I, CD44 antigen, MDU2, Epican, MIC4, CDw44, Extracellular matrix receptor III, ECMR-III, LHR, GP90 lymphocyte homing/adhesion receptor, MDU3
氨基酸序列	QIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIP
蛋白构建	21-220 aa
蛋白纯度	> 90% as determined by SDS-PAGE.
分子量	51.0 kDa (predicted)

内毒素	< 1.0 EU per μg protein as determined by the LAL method.
缓冲液	Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
复溶方法	A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.

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复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

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Desired Reconstitution Concentration

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CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated

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