| T0188 | Fluticasone propionate | Fluticasone propionate, derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist. |
| T0458 | Indometacin | Indomethacin is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of indomethacin is as a Cyclooxygenase Inhibitor. |
| T0693 | Niflumic acid | Niflumic acid is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis. |
| T0942 | Quinacrine dihydrochloride | Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. |
| T0944 | Levamisole hydrochloride | Levamisole hydrochloride is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macropha |
| T11149 | Ecopladib | Ecopladib with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (c |
| T11873 | Lp-PLA2-IN-2 | Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2. |
| T14829 | Bromoenol lactone | Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β; IC50: ~7 μM). It inhibits antigen-stimulated mast |
| T15949 | Mahanimbine | Mahanimbine suppresses the progression of high-fat diet (HFD)-induced metabolic complications in mice. Mahanimbine is an orally active alkaloid from curry leaves. |
| T16751 | Rilapladib | Rilapladib is a selective Lipoprotein-Associated Phospholipase A2 inhibitor (IC50: 230 pM). Rilapladib is also a Platelet Activating Factor Receptor antagonist. |
| T17239 | VU0155069 | VU0155069 strongly inhibits the invasive migration of several cancer cell lines in transwell assays. VU0155069 is a selective phospholipase D1 inhibitor (IC50: 46 nM in vitro). |
| T2044 | Varespladib | Varespladib, a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickl |
| T21969 | ML-095 hydrochloride | ML095 hydrochloride is a specific placental alkaline phosphatase inhibitor. It inhibits PLAP, TNAP and IAP with IC50 of 2.1, >100 and 53 μM, respectively. |
| T2282 | RPI1 | RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. |
| T2907 | Tanshinone I | Tanshinone I, an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells. |
| T2938 | Polydatin | Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum |
| T3417 | Amentoflavone | Amentoflavone, as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflav |
| T3439 | ML348 | ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). |
| T3580 | FIPI | FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell sp |
| T3616 | Carbazochrome | Carbazochrome is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, cea |
| T3640 | GW 4869 | GW4869 is a noncompetitive inhibitor of neutral sphingomyelinase (N-SMase, IC50 of 1 μM). GW4869 is an exosome biogenesis/release inhibitor. |
| T3775 | Armepavine | Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBPß pathways. It improves experimental autoimmune crescentic glom |
| T4192 | hnps-PLA Inhibitor | Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). |
| T4S0590 | Columbin | 1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependen |
| T5454 | ACA | N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. |
| T6109 | Darapladib | Darapladib(IC50=0.25 nM) is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2). |
| T6243 | U73122 | U73122, an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN. |
| T6529 | Halobetasol Propionate | Halobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a t |
| T7280 | CAY10594 | CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis. |
| T8531 | m-3M3FBS | m-3M3FBS is a phospholipase C (PLC) activator. |
| TN3139 | 5alpha-Hydroxycostic acid | 5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate. |
| TN4247 | Ikshusterol 3-O-glucoside | Ikshusterol 3-O-glucoside has a potent snake-venom neutralizing capacity and it might be a potential molecule for the therapeutic treatment for snakebites. |
| TP1299 | Melittin | Melittin, a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low molecul |
| TP1299L | Melittin TFA(20449-79-0(free base)) | Melittin TFA is a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low m |
| TP1299L | Melittin TFA(20449-79-0(free base)) | Melittin TFA is a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low m |
| TQ0105 | CAY10650 | CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM). |
| TQ0159 | U 73343 | U-73122 is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. |
