CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,100 | 5日内发货 | ||
500 μg | ¥ 12,400 | 5日内发货 | ||
1 mg | ¥ 20,700 | 5日内发货 |
生物活性 | Immobilized Human CCR8, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. |
产品描述 | CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. |
种属 | Human |
表达系统 | HEK293 |
标签 | C-mFc |
蛋白编号 | P51685-1 |
别名 | GPR-CY6, CY6, CKRL1, CMKBRL2, TER-1, CDw198, CCR-8, CCR8, CKR-L1, CD198, CMKBR8, ChemR1, TER1, GPRCY6 |
蛋白构建 | Recombinant Human CCR8 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus. It contains Met1-Lys35.[Accession |P51685-1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 30.25 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. |
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CCR8 Protein, Human, Recombinant (mFc) CD-198 GPR-CY6 CY-6 CY6 CMKBRL 2 CKRL 1 GPRCY-6 CKRL1 CKRL-1 CY 6 CMKBR-8 CMKBRL2 TER 1 TER-1 CDw198 CCR-8 CCR8 CCR 8 CKR-L1 GPRCY 6 CD198 CD 198 CMKBR8 ChemR1 CMKBRL-2 TER1 GPRCY6 CMKBR 8 recombinant recombinant-proteins proteins protein