Carboxylesterase 2/CES2 Protein, Human, Recombinant (His)

Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

规格	价格/CNY		数量
50 μg	￥ 3,170	现货
100 μg	￥ 5,610	5日内发货
200 μg	￥ 9,920	5日内发货
500 μg	￥ 20,980	5日内发货

规格

价格/CNY

货期

数量

50 μg

￥ 3,170

现货

100 μg

￥ 5,610

5日内发货

200 μg

￥ 9,920

5日内发货

500 μg

￥ 20,980

5日内发货

生物活性

Measured by its ability to hydrolyze p-nitrophenylacetate. The specific activity is >20000 pmols/min/ug.

产品描述

种属	Human
表达系统	HEK293
标签	His
蛋白编号	O00748-1
别名	carboxylesterase 2, CES2A1, CE-2, PCE-2, iCE
蛋白构建	A DNA sequence encoding the human CES2 isoform 1 (O00748-1) (Met 1-Leu 559) was expressed, with a C-terminal polyhistidine tag.
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	Approxiamtely 60.4 kDa

内毒素	< 1.0 EU per μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from sterile 50mM NaAc, 150mM NaCl, 10% Glycerol, pH 5. 5Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.