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Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)

Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)

产品编号 TMPJ-00601
别名: Apolipoprotein C2, Apolipoprotein C-II, APC2 and APOC2

APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

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Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 13,200 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His) (TMPJ-00601)
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产品描述 APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
种属 Human
表达系统 E. coli
标签 C-6His
蛋白编号 AAP35354.1
别名 Apolipoprotein C2, Apolipoprotein C-II, APC2 and APOC2
氨基酸序列 Thr23-Glu101
蛋白构建 Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Thr23-Glu101 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 14 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

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Keywords

Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His) Apolipoprotein C2 Apolipoprotein C-II APC2 and APOC2 recombinant recombinant-proteins proteins protein

 

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