Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达,激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌、抗疟疾等功效。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 950 | 现货 | ||
5 mg | ¥ 2,320 | 现货 | ||
10 mg | ¥ 3,730 | 现货 | ||
25 mg | ¥ 5,960 | 待询 | ||
50 mg | ¥ 7,880 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,930 | 现货 |
产品描述 | 1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially attributed to DHC. 2. Dehydrocorydaline can inhibit elevated mitochondrial membrane potential in lipopolysaccharide-stimulated macrophages. 3. Dehydrocorydaline has antinociceptive effects in mouse models of inflammatory pain, the effects involve the opioid receptor and inflammatory cytokines. 4. Dehydrocorydaline has anti-inflammatory activity. |
靶点活性 | P. falciparum (3D7 strain):38 nM (IC50) |
别名 | 去氢延胡索甲素硝酸盐, 硝酸脱氢紫堇碱 |
分子量 | 428.44 |
分子式 | C22H24N2O7 |
CAS No. | 13005-09-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (64.19 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.334 mL | 11.6702 mL | 23.3405 mL | 58.3512 mL |
5 mM | 0.4668 mL | 2.334 mL | 4.6681 mL | 11.6702 mL | |
10 mM | 0.2334 mL | 1.167 mL | 2.334 mL | 5.8351 mL | |
20 mM | 0.1167 mL | 0.5835 mL | 1.167 mL | 2.9176 mL | |
50 mM | 0.0467 mL | 0.2334 mL | 0.4668 mL | 1.167 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Dehydrocorydaline nitrate 13005-09-9 Apoptosis Autophagy Chromatin/Epigenetic DNA Damage/DNA Repair MAPK Microbiology/Virology Others Proteases/Proteasome p38 MAPK PARP BCL Caspase Parasite Dehydrocorydaline 13-Methylpalmatine inhibit Inhibitor poly ADP ribose polymerase Dehydrocorydaline Nitrate 去氢延胡索甲素硝酸盐 硝酸脱氢紫堇碱 Bcl-2 Family inhibitor