Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T38665 | OVA-E1 peptide TFA
化合物OVA-E1 peptide TFA
|
1262750-80-0 |
|
|
OVA-E1 peptide TFA 在突变型和野生型胸腺细胞中都能同样地激活 p38 和 JNK 级联。 | ||||
TN3404 | Altholactone
化合物 TN3404
|
65408-91-5 | 98% |
|
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of ... | ||||
TN4394 | Kobophenol A
化合物 TN4394
|
124027-58-3 | 98% |
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell... | ||||
TN3042 | 4-Hydroxycinnamamide
化合物 TN3042
|
194940-15-3 | 98% |
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases. | ||||
TN4938 | Samidin
化合物 TN4938
|
477-33-8 | 98% |
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. | ||||
T78652 | P38α inhibitor 4
化合物 p38α inhibitor 4
|
1262406-08-5 | 98% |
|
p38α inhibitor4(化合物10)作为一种选择性变构p38α抑制剂,呈现出对p38α的高度选择性,其IC50值为1.2 μM。该化合物对p38β、p38γ及p38δ均无活性。 | ||||
T78838 | Akt/NF-κB/MAPK-IN-1
化合物 Akt/NF-κB/MAPK-IN-1
|
98% |
|
|
Akt/NF-κB/MAPK-IN-1(compound 2m)为口服活性NO抑制剂,IC50值为7.70 μM,低毒性。该化合物通过抑制Akt/NF-κB与MAPK信号通路实现抗炎效应。 | ||||
T79028 | P38 Kinase inhibitor 4
化合物 p38 Kinase inhibitor 4
|
13142-47-7 | 98% |
|
p38 Kinase inhibitor 4 (compound 135) 是高效的 p38 MAP Kinase 抑制剂,具有显著的生物活性。 | ||||
T80631 | Esculin sesquihydrate
化合物 Esculin sesquihydrate
|
66778-17-4 | 98% |
|
Esculin sesquihydrate为荧光香豆素葡萄糖苷类化合物,源自灰树皮有效成分。该化合物可经MAPK信号通路改善实验性糖尿病肾病(DN)的认知障碍,并具有抗氧化应激及抗炎效应。 | ||||
T81441 | PLK1/p38γ-IN-1
化合物 PLK1/p38γ-IN-1
|
2418614-81-8 | 98% |
|
PLK1/p38γ-IN-1(化合物14)为PLK1与p38γ多靶点抑制剂,体外有效抑制人肝细胞癌与肝母细胞瘤细胞增殖。 | ||||
T81598 | Org OD 02-0
化合物 Org OD 02-0
|
13258-85-0 | 98% |
|
Org OD 02-0(10-Ethenyl-19-norprogesterone)为mPRα(膜孕酮受体α)特异性激动剂,IC50值为33.9 nM。该化合物能够激活MAPK活性,并且能抑制催乳素(PRL)的分泌。 | ||||
TN4317 | Isopedicin
化合物 TN4317
|
4431-42-9 | 98% |
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr... | ||||
TN5011 | Shizukaol B
化合物 TN5011
|
142279-40-1 | 98% |
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl... | ||||
T7162 | R1487 Hydrochloride
化合物R1487 (Hydrochloride)
|
449808-64-4 | 98% |
|
R1487 Hydrochloride (R1487(Hydrochloride)) 是一种可口服的高选择性 p38α 抑制剂,对 p38α 和 p38β 的Kd 值分别为 0.2 nM 和 29 nM。 | ||||
T10298 | AMG-548 hydrochloride (864249-60-5 free base)
化合物 T10298
|
T10298 | 98% |
|
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective a... | ||||
TN4774 | Physalin A
化合物 TN4774
|
23027-91-0 | 98% |
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc... | ||||
TN1751 | Hydroxycitric acid
2-羟基柠檬酸
|
6205-14-7 | 98% |
|
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to ac... | ||||
TN1347 | 8-Prenylkaempferol
化合物8-Prenylkaempferol
|
28610-31-3 | 98% |
|
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-in... | ||||
TN4986 | Selinidin
化合物 TN4986
|
19427-82-8 | 98% |
|
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation. | ||||
TN5174 | Trichosanatine
化合物 TN5174
|
169626-16-8 | 98% |
|
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine... |