CYPA Protein, Human, Recombinant

Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.

规格	价格/CNY		数量
10 μg	￥ 220	5日内发货
50 μg	￥ 700	5日内发货
500 μg	￥ 4,740	5日内发货
1 mg	￥ 7,510	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 220

5日内发货

50 μg

￥ 700

5日内发货

500 μg

￥ 4,740

5日内发货

1 mg

￥ 7,510

5日内发货

产品描述

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P62937
别名	Rotamase A, Peptidyl-prolyl cis-trans isomerase A, PPIase A, PPIA, Cyclophilin A, Cyclosporin A-binding protein, SP18, CYPA
氨基酸序列	Met1-Glu165
蛋白构建	Met1-Glu165
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	16 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.

计算器

复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

bottom

CYPA Protein, Human, Recombinant

计算器

技术支持

Keywords