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转化生长因子-β 家族

转化生长因子-β (Transforming Growth Factor-β, TGF-β) 是一种多功能细胞因子,属于转化生长因子超家族,包括三种不同的哺乳动物亚型(TGF-β 1~3,HGNC编号TGFB1、TGFB2、TGFB3)和许多其他信号蛋白。TGFB 蛋白由所有白细胞谱系产生。活化的 TGF-β 复合物与其他因子形成与 TGF-β 受体结合的丝氨酸/苏氨酸激酶复合物。TGF-β受体由1型和2型受体亚基组成。TGF-β结合后,2型受体激酶磷酸化并激活1型受体激酶,从而激活信号级联反应。TGF-β在干细胞分化以及T细胞调控和分化中也起着至关重要的作用。由于其在免疫和干细胞调控和分化中的作用,它是癌症、自身免疫性疾病和传染病领域中研究最多的细胞因子。

目录号 产品名/同用名 种属 表达系统
TMPJ-00100 Artemin Protein, Human, Recombinant Human E. coli
TMPJ-00238 Lefty-A Protein, Human, Recombinant (His) Human Human Cells
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
TMPJ-00255 TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
TMPJ-00256 Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
TMPJ-00259 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
TMPJ-00260 Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
TMPJ-00271 SMAD3 Protein, Human, Recombinant (His & Flag) Human E. coli
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
TMPJ-00663 GDF-8 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat Human Cells
TMPJ-00713 GDF-11 Protein, Human, Recombinant Human Human Cells
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse Human Cells
TMPJ-00966 GDF-5 Protein, Human, Recombinant Human E. coli
TMPJ-01015 INHBC Protein, Human, Recombinant (C-His) Human Human Cells
TMPJ-01016 INHBC Protein, Human, Recombinant (N-His) Human E. coli
TMPJ-01108 SMAD4 Protein, Human, Recombinant (His) Human E. coli
TMPJ-01226 Irisin Protein, Human/Mouse/Rat, Recombinant (hFc) Human,Mouse,Rat Human Cells
TMPJ-01227 Irisin Protein, Human/Mouse/Rat, Recombinant (C-His) Human,Mouse,Rat Human Cells
TMPJ-01228 Irisin Protein, Human/Mouse/Rat, Recombinant (N-His) Human,Mouse,Rat Human Cells
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