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The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.
TargetMol
1 2
Cat. No. Product Name CAS No. Purity Chemical Structure
TN1338 7Beta-Hydroxycholesterol
胆甾-5-烯-3,7二醇
566-27-8 98%
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells...
TN5057 Stachybotramide
化合物 TN5057
149598-71-0 98%
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipo...
TN3989 Erycibelline
化合物 TN3989
107633-95-4 98%
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
TN3675 Cleomiscosin C
化合物 TN3675
84575-10-0 98%
Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM...
TN1801 Isosalvianolic acid C
异丹酚酸C
142115-17-1 98%
Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .
TN5174 Trichosanatine
化合物 TN5174
169626-16-8 98%
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine...
TN3397 Alpinumisoflavone
化合物 TN3397
34086-50-5 98%
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is e...
TN1868 Ligupurpuroside A
紫茎女贞苷 A
147396-01-8 98%
Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L.
TN1869 Ligupurpuroside B
紫茎女贞苷 B
147396-02-9 98%
Ligupurpuroside B has antioxidant activity.
TN5097 Tanshindiol C
化合物 TN5097
97465-71-9 98%
Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therap...
TN1836 Kudinoside D
苦丁冬青苷 D
173792-61-5 99.88%
Kudinoside D 是 Ilex kudingcha 中三萜皂苷的主要天然成分之一。它能够调节 3T3-L1 脂肪细胞中 AMPK 途径,并可抑制脂肪形成。
TN1244 3'-Demethylnobiletin
3'-去甲川陈皮素
112448-39-2 99.87%
3'-Demethylnobiletin 是样一种存在于柑橘类水果中的多甲氧基黄酮类化合物,是一种 Nobiletin 的衍生物。N 其中 obiletin 能够调节 Src,FAK 和 STAT3 信号传导来抗肿瘤,并能够抑制肿瘤血管生成。
T20887 Atorvastatin Sodium
阿伐他汀钠
134523-01-6 99.79%
Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂,增加肝细胞上低密度脂蛋白(LDL)受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。
TN2208 Siamenoside I
翅子罗汉果I
126105-12-2 99.79%
Siamenoside I 是一种罗汉果甜甙,具有多种生物学功能。
TN1136 Procyanidin A1
原花青素 A1
103883-03-0 99.23%
Procyanidin A1 (Proanthocyanidin A1) 是一种原花青素二聚体,具有抗过敏作用,可抑制蛋白激酶 C 激活下游脱粒或 RBL-213 细胞内部储存的 Ca2+流入。
TN1134 Euscaphic acid
野鸦椿酸
53155-25-2 98.93%
Euscaphic acid 是来源于枣的一种三萜,是DNA 聚合酶抑制剂,可诱导细胞凋亡。它抑制小牛 DNA 聚合酶 α 和大鼠 DNA 聚合酶 β 的IC50值分别为 61 和 108 μM。
T4179 Probucol disuccinate
普罗布考
216168-45-5 98.61%
Probucol disucinate 是一种 Probucol 的衍生物。其中 Probucol 是脂质调节的化合物,它能降低 LDL-cholesterol 水平。
T25701 Levosemotiadil
左司莫地尔
116476-16-5 98.47%
Levosemotiadil(SA 3212) 是一种新型钙拮抗剂,是一种非常有效的低密度脂蛋白氧化抑制剂。Levosemotiadil 可用于预防致死性心律失常。
TN1160 1,2,3,6-Tetragalloylglucose
1,2,3,6-四-O-没食子酰-Β-D-葡萄糖
79886-50-3 98.43%
1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员,是多肽A1 的抑制剂(Ki:1.68 μM)。
T0022 Taurine
牛磺酸
107-35-7 98.05%
Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。
7Beta-Hydroxycholesterol
TN1338
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells...
Stachybotramide
TN5057
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipo...
Erycibelline
TN3989
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
Cleomiscosin C
TN3675
Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM...
Isosalvianolic acid C
TN1801
Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .
Trichosanatine
TN5174
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine...
Alpinumisoflavone
TN3397
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is e...
Ligupurpuroside A
TN1868
Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L.
Ligupurpuroside B
TN1869
Ligupurpuroside B has antioxidant activity.
Tanshindiol C
TN5097
Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therap...
Kudinoside D
TN1836
Kudinoside D 是 Ilex kudingcha 中三萜皂苷的主要天然成分之一。它能够调节 3T3-L1 脂肪细胞中 AMPK 途径,并可抑制脂肪形成。
3'-Demethylnobiletin
TN1244
3'-Demethylnobiletin 是样一种存在于柑橘类水果中的多甲氧基黄酮类化合物,是一种 Nobiletin 的衍生物。N 其中 obiletin 能够调节 Src,FAK 和 STAT3 信号传导来抗肿瘤,并能够抑制肿瘤血管生成。
Atorvastatin Sodium
T20887
Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂,增加肝细胞上低密度脂蛋白(LDL)受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。
Siamenoside I
TN2208
Siamenoside I 是一种罗汉果甜甙,具有多种生物学功能。
Procyanidin A1
TN1136
Procyanidin A1 (Proanthocyanidin A1) 是一种原花青素二聚体,具有抗过敏作用,可抑制蛋白激酶 C 激活下游脱粒或 RBL-213 细胞内部储存的 Ca2+流入。
Euscaphic acid
TN1134
Euscaphic acid 是来源于枣的一种三萜,是DNA 聚合酶抑制剂,可诱导细胞凋亡。它抑制小牛 DNA 聚合酶 α 和大鼠 DNA 聚合酶 β 的IC50值分别为 61 和 108 μM。
Probucol disuccinate
T4179
Probucol disucinate 是一种 Probucol 的衍生物。其中 Probucol 是脂质调节的化合物,它能降低 LDL-cholesterol 水平。
Levosemotiadil
T25701
Levosemotiadil(SA 3212) 是一种新型钙拮抗剂,是一种非常有效的低密度脂蛋白氧化抑制剂。Levosemotiadil 可用于预防致死性心律失常。
1,2,3,6-Tetragalloylglucose
TN1160
1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员,是多肽A1 的抑制剂(Ki:1.68 μM)。
Taurine
T0022
Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。
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